Deficiency of the essential nutrients lysine, methionine, threonine and vitamins A, E, C significantly increases the mutagenic environment of somatic cells in growing Wag rats. Aflatoxin B1 produces a pronounced mutagenic effect on the cellular genetic apparatus; this effect is substantially modified due to the nutrition character: it is either intensified or inhibited. The results obtained suggest that the nutritional factors can de used for prevention and elimination of aflatoxin B1-induced mutations.
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