The method of cyanoacrylate ablation of varicose veins is currently considered as a possible alternative to traditional methods of thermal obliteration. One of significant advantages of this method is no need for performing tumescent anaesthesia. Over the period from 1995 to 2002, cyanoacrylate obliteration of varicose veins was carried out in a total of 96 patients, with clinical assessment of the complication rate and efficacy at various time intervals, with the maximum follow-up period amounting to 3 years. In addition to clinical assessment of the results, presented are the findings of histological examinations of morphological changes occurring in the venous wall and lumen after administration of cyanoacrylate on days 3, 7, 10, 14, 21, 30 and 90. The conclusion was drawn on feasibility of carrying out prospective studies on using various glue compositions of both Russian and foreign manufacture in order to determine all benefits and disadvantages of this group of chemical compounds for more successful and wider implementation of them into clinical practice of modern phlebology.
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