In a recent paper, Grafen (2018) discussed the left-hand side in the equation stating Fisher's (1930, 1958) "Fundamental Theorem of Natural Selection" (FTNS). Fisher's original statement of the FTNS is, in effect, "The rate of increase in fitness of any organism is equal to its genetic variance in fitness at that time" with the rate of increase in fitness understood as the one "due to all changes in gene ratios" (Fisher, 1930, p. 35). For purposes of exposition, Grafen (2018) considered what is today called the analogous discrete-time model, and restated the FTNS on p. 181 as "The increase in population [mean fitness] due to changes in gene frequencies [is equal to the] additive genetic variance in fitness [divided by the] mean fitness". Allowing for the fact that Grafen's statement of the FTNS relates to a discrete-time model, his statement is in effect a discrete-time version of Fisher's. It has however been widely accepted for many years, ever since Price's (1972) deep analysis of the FTNS, that Fisher's wording does not correctly describe the content of the FTNS. The same is therefore true of Grafen's statement. The confusion caused by these misstatements is unfortunate and adds to a continuing misunderstanding of the FTNS, whose source can also be found in Fisher's (1941) own explanation. Our purpose is to review the detailed analysis of the calculations leading to the FTNS to clarify the points at issue.
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http://dx.doi.org/10.1016/j.jtbi.2019.04.014 | DOI Listing |
J Med Case Rep
January 2025
Department of Clinical Medicine, Jining Medical University, Jining, China.
Background: Superficial acral fibromyxoma is a noncancerous, benign tumor of soft tissue with an unidentified origin. Occurrences of abnormalities on the palm are less frequently documented.
Case Report Presentation: A 47-year-old East Asian woman presented with a palm tumor on her left knuckle that had been present for 4 months.
Int J Surg Case Rep
December 2024
Upper extremity trauma and Microsurgery Department, 108 Military Central Hospital, 1 Tran Hung Dao Street, Hanoi, Viet Nam.
Introduction: Reconstruction for open multiple transmetacarpal amputation secondary to a crushing injury is really challenging. Some treatment approaches could be proposed. To avoid the drawbacks of a prosthesis and hand transplantation such as the high cost, and long-term side effects of anti-rejection drugs, toe transfers were chosen.
View Article and Find Full Text PDFJ Exp Child Psychol
December 2024
BCL, CNRS, Université Côte d'Azur, Nice, France. Electronic address:
When processing serial information, adults tend to map elements of a sequence onto a mental horizontal line, following the direction of their reading and writing system. For example, in a Western population, the beginning of a series is associated with the left-hand side of the mental line, while its end is preferentially associated with the right. To complete the few studies that have investigated the cultural vs.
View Article and Find Full Text PDFAnat Sci Int
December 2024
Department of Anatomical Sciences, Afzalipour School of Medicine, Kerman University of Medical Sciences, Kerman, Iran.
Zhonghua Wai Ke Za Zhi
December 2024
Pediatric Orthopedics Department, Beijing Jishuitan Hospital, Capital Medical University,Beijing100035,China.
To explore the interrelationship among three simplified hand and wrist bone age assessment methods and to establish corresponding bone ages for each substage in male children. This retrospective case series study included 169 left hand and wrist X-rays from 152 male children who underwent bone age assessments at the Pediatric Orthopedics and Pediatrics Departments,Beijing Jishuitan Hospital,Capital Medical University from January 2019 to December 2023. The age at the time of X-ray was (13.
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