AI Article Synopsis

  • The review focuses on the management challenges faced by patients with cystine stones, highlighting their high recurrence rates and the need for effective interventions.
  • Studies showed that patients underwent an average of 5.7 surgical procedures over a long follow-up period of nearly 10 years, with a notable rise in a specific surgical technique (RIRS).
  • Despite medical management, these patients still require regular interventions, and there is a need for better data on the overall impact on their kidney function and more comprehensive patient records.

Article Abstract

Purpose Of Review: Cystine stone patients can be difficult to manage with frequent recurrences. We performed a systematic review with a view to assessing interventions, compliance and their long-term outcomes.

Recent Findings: Ten retrospective observational studies (253 patients) assessed the outcomes and long-term follow-up of cystine stone patients. The mean length of follow-up was 9.6 years (range 3.5-21.8 years). The overall mean number of surgical procedures/patient was 5.7 (range 2-9.8/patient) with the overall mean number of surgical procedures/patient/year at 0.59 (range 0.22-1.32/patient/year). While open surgery has decreased over the last decade and PCNL has been stable, there seems to be a rise of RIRS during this period. Patients with cystine stones need periodic interventions for stone recurrences despite medical management, with limited data showing the impact on renal function. While the management is individualised, wide variability exists with often poor and incomplete patient data.

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Source
http://dx.doi.org/10.1007/s11934-019-0891-7DOI Listing

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