Development of multiple organ dysfunction syndrome in older and young adult trauma patients.

Int J Crit Illn Inj Sci

Department of Emergency Medicine, Adventhealth Tampa/US Acute Care Solutions, Tampa, Florida, USA.

Published: January 2019

Objective: We sought out to determine the correlation between the injury severity score (ISS) and multiple organ dysfunction syndrome (MODS) between severely injured young adults (18-54 years) and elderly (>55 years) patients.

Materials And Methods: This was a cross-sectional observational study. We included all adult cases (>18 years) diagnosed with trauma defined by the International Classification of Diseases, Ninth Revision. For significance testing, Chi-square test and odds ratio were used. Severe injuries were defined by an ISS >15. The presence of MODS was based on the definitions proposed by society for critical care medicine.

Results: A total of 469 young and 173 elderly patients were included in the study. Among the 469 young adults, 193 had ISS >15, whereas out of the 173 elderly patients, 88 had an ISS >15. Severely injured young and elderly groups were more likely to develop MODS compared with those with an ISS <15 ( < 0.001 and < 0.001, respectively). The elderly had a higher likelihood of developing MODS ( < 0.001; odds ratio: 5.17; 95% confidence interval: 2.74-9.80).

Conclusion: This study demonstrated a direct relationship between an ISS >15 and the development of MODS. We also observed a five-fold increase in the development of MODS among severely injured elderly patients.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6423931PMC
http://dx.doi.org/10.4103/IJCIIS.IJCIIS_56_18DOI Listing

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