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http://dx.doi.org/10.1001/jama.2019.3471 | DOI Listing |
Cardiovasc Diabetol
July 2021
Division of Endocrinology and Metabolic Diseases, Department of Advanced Medical and Surgical Sciences, University of Campania Luigi Vanvitelli, Naples, Italy.
Lower extremity amputations (LEA) are associated with a high mortality and medical expenditure. Diabetes accounts for 45% to 70% of LEA and is one of the most potent risk factors for peripheral artery diseases (PAD). The existence of a link between the recent relaxation of glycemic targets and the resurgence of LEA is suggested from the analysis of adult participants in the National Health and Nutrition Examination Survey (NHANES) between 2010 and 2015, when diabetes-related LEA increased by more than 25% associated with a decline in glycemic control.
View Article and Find Full Text PDFCurr Opin Cardiol
September 2020
Department of Medicine, Brigham and Women's Hospital Heart and Vascular Center, Harvard Medical School, Boston, Massachusetts, USA.
Purpose Of Review: There has been a recent resurgence of diabetes-related cardiovascular complications after years of steady improvement. This review highlights established and emerging contemporary secondary prevention approaches that lower the risk of atherosclerotic and nonatherosclerotic cardiovascular disease events among patients with diabetes.
Recent Findings: Secondary prevention therapies modify residual risk targets, including cardiometabolic pathways, lipoproteins, thrombosis, and inflammation.
JAMA
May 2019
Epidemiology and Statistics Branch, Division of Diabetes Translation, US Centers for Disease Control and Prevention, Atlanta, Georgia.
Diabetes Care
January 2019
Division of Diabetes Translation, Centers for Disease Control and Prevention, Atlanta, GA
Objective: To determine whether declining trends in lower-extremity amputations have continued into the current decade.
Research Design And Methods: We calculated hospitalization rates for nontraumatic lower-extremity amputation (NLEA) for the years 2000-2015 using nationally representative, serial cross-sectional data from the Nationwide Inpatient Sample on NLEA procedures and from the National Health Interview Survey for estimates of the populations with and without diabetes.
Results: Age-adjusted NLEA rates per 1,000 adults with diabetes decreased 43% between 2000 (5.
Curr Diab Rep
August 2016
Section of General Internal Medicine, Chicago Center of Diabetes Translation Research, MacLean Center for Clinical Medical Ethics, University of Chicago, Chicago, IL, USA.
The recent resurgence of social and civic disquiet in the USA has contributed to increasing recognition that social conditions are meaningfully connected to disease and death. As a "lifestyle disease," control of diabetes requires modifications to daily activities, including healthy dietary practices, regular physical activity, and adherence to treatment regimens. One's ability to develop the healthy practices necessary to prevent or control type 2 diabetes may be influenced by a context of social disorder, the disruptive social and economic conditions that influence daily activity and, consequently, health status.
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