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Involvement of the parabrachial nucleus in emergence from general anesthesia.
Front Neurosci
December 2024
Department of Anesthesiology, West China Hospital, Sichuan University, Chengdu, China.
The parabrachial nucleus (PBN), located in the dorsolateral pons, is involved in many important biological functions, such as sensory signaling, feeding, defensive behaviors, fear, anxiety, and sleep-wake cycles. General anesthesia shares the classical feature of reversible loss of consciousness with natural sleep, and accumulating evidence has indicated that general anesthesia and sleep-wake behaviors share some common underlying neural mechanism. In recent years, emerging studies have investigated the involvement of PBN in emergence from general anesthesia, but divergence exists in terms of different types of general anesthetics or different durations of treatment with the same group of general anesthetics.
View Article and Find Full Text PDFSegmental Thoracic Spinal Anesthesia for Critical Patients Undergoing Abdominal Surgeries: A Case Series and Literature Review.
Cureus
November 2024
Department of Anesthesia and Critical Care, Al-Ahli Hospital, Hebron, PSE.
Segmental thoracic spinal anesthesia (STSA) is emerging as a promising alternative for high-risk patients undergoing abdominal surgeries, particularly those who are not optimal candidates for general anesthesia (GA). By selectively targeting the thoracic spinal segments responsible for abdominal innervation, STSA aims to provide precise anesthesia and pain management while minimizing systemic side effects. This case series presents the outcomes of several critical patients who underwent abdominal surgeries under STSA.
View Article and Find Full Text PDFA considerable portion of the global population is affected by pulpitis and periapical lesions. While the impact of infections caused by various microbes and host effector molecules in pulpal and periapical diseases is widely recognized, disease susceptibility and progression are also influenced by the dynamic interaction between host genetic factors and environmental influences. Apical periodontitis occurs as an inflammatory response to microorganisms present in the root canals of infected teeth.
View Article and Find Full Text PDFThe nociceptive withdrawal reflex during spinal analgesia in pigs undergoing veno-arterial extracorporeal membrane oxygenation: a prospective observational study.
Front Vet Sci
December 2024
Experimental Surgery Facility, Experimental Animal Center, Faculty of Medicine, University of Bern, Bern, Switzerland.
Introduction: Use of veno-arterial extracorporeal membrane oxygenation (VA-ECMO) is still in the focus of research, in which pigs are commonly involved. During VA-ECMO, cardiovascular parameters are artificially manipulated and therefore not reliable indicators of nociception. Nociceptive withdrawal reflex (NWR) thresholds can be a suitable alternative in such a context.
View Article and Find Full Text PDFAssessing the Use and Acceptability of Virtual Reality to Assist Coping in Children Undergoing Clinical Procedures.
J Spec Pediatr Nurs
January 2025
Department of Anesthesia and Pain Medicine, Perth Children's Hospital, Perth, Western Australia, Australia.
Purpose: Virtual reality is used as a distraction tool during medical procedures that can cause anxiety and pain. We assessed the usefulness, engagement, value and feasibility of virtual reality to help children cope with routine clinical procedures.
Design And Methods: Quality improvement study.
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