Adaptive learning systems have received an increasing attention as they enable to provide personalized instructions tailored to the behaviors and needs of individual learners. In order to reach this goal, it is desired to have an assessment system, monitoring each learner's ability change in real time. The Elo Rating System (ERS), a popular scoring algorithm for paired competitions, has recently been considered as a fast and flexible method that can assess learning progress in online learning environments. However, it has been argued that a standard ERS may be problematic due to the multidimensional nature of the abilities embedded in learning materials. In order to handle this issue, we propose a system that incorporates a multidimensional item response theory model (MIRT) in the ERS. The basic idea is that instead of updating a single ability parameter from the Rasch model, our method allows a simultaneous update of multiple ability parameters based on a compensatory MIRT model, resulting in a multidimensional extension of the ERS ("M-ERS"). To evaluate the approach, three simulation studies were conducted. Results suggest that the ERS that incorrectly assumes unidimensionality has a seriously lower prediction accuracy compared to the M-ERS. Accounting for both speed and accuracy in M-ERS is shown to perform better than using accuracy data only. An application further illustrates the method using real-life data from a popular educational platform for exercising math skills.
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http://dx.doi.org/10.3389/fpsyg.2019.00620 | DOI Listing |
Biomed Pharmacother
January 2025
Pharmacology, Toxicology and Biochemistry Department, Faculty of Pharmacy, Future University in Egypt (FUE), Cairo, Egypt; Pharmacology and Toxicology Department, Faculty of Pharmacy, Cairo University, Cairo, Egypt.
While cognitive impairment has been documented in ulcerative colitic patients, the possible influence of central β3-adrenergic receptor (β3-AR) signaling on this extraintestinal manifestation remains unclear. Previously, we identified an imperative role for mirabegron (MA) as an agonist of β3-AR, in decreasing the BACE-1/beta-amyloid (Aβ) cue in the colons of UC rats. Consequently, we investigated its therapeutic potential for alleviating cognitive impairment associated with UC.
View Article and Find Full Text PDFBMJ Open
December 2024
Perinatal HIV Research Unit (PHRU), University of the Witwatersrand Johannesburg, Johannesburg, Gauteng, South Africa.
Purpose: In the setting of an established childhood pneumococcal vaccination programme with immediate initiation and treatment of antiretroviral therapy (ART) for people living with HIV (PLWH), the risk of adult pneumococcal community-acquired pneumonia (CAP) is not recently described. We aimed to investigate CAP incidence, recurrence, mortality, risk factors and microbiology before and during the COVID-19 pandemic.
Participants: Adults aged ≥18 years were enrolled in three South African provinces from March 2019 to October 2021, with a brief halt during the initial COVID-19 lockdown.
Biol Trace Elem Res
January 2025
Department of Geriatrics, The Second Affiliated Hospital, Nanjing Medical University, Nanjing, 210011, China.
Several studies have reported associations between specific heavy metals and essential trace elements and acute myocardial infarction (AMI). However, there is limited understanding of the relationships between trace elements and AMI in real-life co-exposure scenarios, where multiple elements may interact simultaneously. This cross-sectional study measured serum levels of 56 trace elements using inductively coupled plasma mass spectrometry.
View Article and Find Full Text PDFCureus
December 2024
Genetics Unit, Laboratory Department, Al Hada Armed Forces Hospital, Taif, SAU.
An aggressive angiomyxoma (AA) is a rare soft tissue neoplasm of the lower female genital tract. The incidence of vaginal involvement is low, so it is commonly misdiagnosed as a Bartholin cyst, lipoma, and abscess, among others. This is a case of a 31-year-old female patient presenting with anterior vaginal wall swelling measuring 1 x 1 cm, clinically diagnosed as vaginal carbuncle.
View Article and Find Full Text PDFBackground: Though European Respiratory Society and American Thoracic Society (ERS/ATS) guidelines for pulmonary function test (PFT) interpretation recommend the use of the forced vital capacity (FVC) lower limit of normal (LLN) to exclude restriction, recent data suggest that the negative predictive value (NPV) of the FVC LLN is lower than has been accepted, particularly among non-Hispanic Black patients. Using a machine learning (ML) model-rather than the FVC LLN-to exclude restriction may improve the accuracy and equity of PFT interpretation. We sought to develop and externally validate a ML model to predict restriction from spirometry and to assess the potential impact of this model on PFT interpretation.
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