Human Monkeypox: Epidemiologic and Clinical Characteristics, Diagnosis, and Prevention.

Infect Dis Clin North Am

Division of Infection and Immunity, Center for Clinical Microbiology, University College London, The National Institute of Health Research Biomedical Research Centre at UCL Hospitals, Gower Street, London WC1E 6BT, UK.

Published: December 2019

AI Article Synopsis

  • - Recent outbreaks of human monkeypox virus have raised concerns due to its severe symptoms, which can resemble smallpox.
  • - A notable increase in monkeypox cases has been observed in West and Central Africa, particularly affecting individuals under 40 who have no immunity from prior smallpox vaccinations.
  • - The article explores the epidemiology, clinical characteristics, and treatment of monkeypox, highlighting its increasing risk to public health.

Article Abstract

Recently, concern has been raised about the emergence of human monkeypox virus and the occasionally severe clinical presentation bearing resemblance to that of smallpox. In 2018 3 patients in the UK were diagnosed with monkeypox, and the frequency and geographic distribution of cases across West and Central Africa have increased in recent years. In Nigeria, most monkeypox patients are aged <40 years and lack cross-protective immunity because they were born after discontinuation of the smallpox eradication campaign. This article reviews the epidemiology, clinical features, and management of monkeypox and discusses its growing public health threat in this context.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9533922PMC
http://dx.doi.org/10.1016/j.idc.2019.03.001DOI Listing

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