AI Article Synopsis
- - The text discusses target lesions associated with Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN), outlining their clinical presentation and classification.
- - It categorizes lesions based on characteristics like shape, fever, mucosal ulcerations, and joint pain, while also considering histological and lab findings.
- - An algorithmic approach is provided for clinicians to accurately diagnose patients with these lesions, helping them distinguish between severe conditions and less serious skin issues.
Article Abstract
We have explored the rash that appears as target lesions, with the central and dominant diseases belonging to the Stevens-Johnson syndrome/toxic epidermal necrolysis group. After presenting the clinical patterns of an individual target lesion and classifying them into different types of lesions, the contribution has been organized with groups characterized by such specific findings according to the type of lesion: flat or raised, typical or atypical, presence or absence of fever, presence or absence of mucosal ulcerations, presence or absence of arthralgias, and/or internal organ involvement. Other specific features, such as histologic appearance, immunofluorescence findings, and laboratory changes, are considered. We provide clinicians with an algorithmic, systematic, and logical approach to diagnose the condition of the patients who present with targetoid lesions, and enable them to differentiate between those with serious systemic and life-threatening diseases from others with ordinary skin ailments.
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| http://dx.doi.org/10.1016/j.clindermatol.2018.12.008 | DOI Listing |
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