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Risk factors and protective measures for desmoid tumours in familial adenomatous polyposis: retrospective cohort study.
BJS Open
December 2024
Unit of Hereditary Digestive Tract Tumours, Fondazione IRCCS Istituto Nazionale dei Tumouri, Milan, Italy.
Background: Familial adenomatous polyposis is a cancer-predisposing syndrome caused by germline pathogenic variants of the adenomatous polyposis coli gene, leading to numerous colorectal polyps and a high risk of colorectal cancer. Desmoid tumours have become significant in the management of familial adenomatous polyposis after a colectomy, yet the exact incidence remains undetermined due to a lack of dedicated surveillance.
Methods: This retrospective study accessed data from the prospectively maintained Hereditary Digestive Tumours Registry from 2000 to 2023.
Desmoid fibromatosis post-cervical spine surgical intervention.
BJR Case Rep
January 2025
Dubai Health, Dubai 1853, United Arab Emirates.
Article Synopsis
- Desmoid tumours are rare benign growths that can aggressively invade surrounding tissues, especially near nerves and blood vessels, making them difficult to treat.
- Their exact cause is unknown, but they are more common in females and may be linked to factors like trauma, surgery, or inflammation, suggesting possible genetic or hormonal influences.
- A case study highlights a 34-year-old woman who developed a desmoid tumour in her neck after neck surgery; despite surgical removal, the tumour recurred, necessitating a second operation for complete treatment.
Familial adenomatous polyposis family with clustering of psychiatric disorders.
Jpn J Clin Oncol
January 2025
Department of Clinical Oncology, Graduate School of Medicine, Akita University, Hondo 1-1-1, Akita, 010-8543, Japan.
Article Synopsis
- Familial adenomatous polyposis (FAP) is an inherited disorder caused by mutations in the APC gene, leading to colorectal polyps and other health issues.
- This condition can also cause extracolonic manifestations like desmoid tumors and various mental disorders in affected families.
- A case study highlights the importance of mental health care in genetic counseling, as a family with FAP showed connections between the disorder and mental health issues, including autism spectrum disorder and intellectual disabilities.
Breast Desmoid Tumours: A Review of the Literature.
Breast J
January 2025
Australian National University School of Medicine and Psychology, Canberra, ACT 2600, Australia.
Breast desmoid tumour is a rare type of benign breast disease that presents like malignancy. Current guidelines are based on limited evidence derived from case reports and small case series and recommend resection with microscopically-negative margin (R0). There is a high risk of recurrence despite negative surgical margins.
View Article and Find Full Text PDFDesmoid-type fibromatosis of the breast in a male patient following cosmetic surgery: a rare case report.
Front Oncol
December 2024
Angeles Breast Center, Hospital Ángeles Valle Oriente, San Pedro Garza Garcia, Nuevo Leon, Mexico.
Background: Desmoid-type fibromatosis of the breast is a rare, benign, but locally aggressive tumor that typically affects women. Its presentation in male patients is exceedingly rare, and even more so following a cosmetic procedure such as liposuction. This case report describes a unique presentation of breast fibromatosis in a male patient, who developed the condition after undergoing liposuction for cosmetic purposes to define the pectoral area.
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