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Generalized lymphatic anomaly in a pediatric patient manifesting as a rare presentation of hemorrhagic pleural effusion: a case report.
BMC Pediatr
January 2025
Department of Pediatrics, Huazhong University of Science and Technology Union Shenzhen Hospital, Shenzhen, China.
Background: Generalized lymphatic anomaly (GLA) is a rare congenital lymphatic malformation (LM) characterized by multiple infiltrating lymphangiomas in various tissues. Owing to its rarity, information on this disease is obtained mainly through case reports, leading to delayed diagnosis. In this study, we reported a case of generalized lymphatic anomaly in a pediatric patient manifesting as hemorrhagic pleural effusion.
View Article and Find Full Text PDFA coopetition-driven strategy of parallel/perpendicular aromatic stacking enabling metastable supramolecular polymerization.
Nat Commun
December 2024
School of Chemistry and Chemical Engineering, Northwestern Polytechnical University, Xi'an, 710072, China.
Metastable supramolecular polymerization under kinetic control has recently been recognized as a closer way to biosystem than thermodynamic process. While impressive works on metastable supramolecular systems have been reported, the library of available non-covalent driving modes is still small and a simple yet versatile solution is highly desirable to design for easily regulating the energy landscapes of metastable aggregation. Herein, we propose a coopetition-driven metastability strategy for parallel/perpendicular aromatic stacking to construct metastable supramolecular polymers derived from a class of simple monomers consisting of lateral indoles and aromatic core.
View Article and Find Full Text PDFOptimization of Cocoa Pods Maturity Classification Using Stacking and Voting with Ensemble Learning Methods in RGB and LAB Spaces.
J Imaging
December 2024
Laboratoire Imagerie et Vision Artificielle (ImVia), Université de Bourgogne, 21000 Dijon, France.
Determining the maturity of cocoa pods early is not just about guaranteeing harvest quality and optimizing yield. It is also about efficient resource management. Rapid identification of the stage of maturity helps avoid losses linked to a premature or late harvest, improving productivity.
View Article and Find Full Text PDFInvestigation of Mechanical Properties and Color Changes of 3D-Printed Parts with Different Infill Ratios and Colors After Aging.
Materials (Basel)
December 2024
Scientific and Technological Research Center, Duzce University, Duzce 81620, Türkiye.
Since their inception, plastics have become indispensable materials. However, plastics used for extended periods in industrial applications are prone to aging, which negatively impacts their material behavior and performance. To ensure the long-term usability of these materials, they must be tested in real-time, in-service environments to assess degradation.
View Article and Find Full Text PDFValidation of Therapeutic Agent Conjugation to Polyvinyl Alcohol-Coated Medical Devices.
J Vis Exp
November 2024
Department of Molecular and Cellular Physiology, LSU Health Shreveport.
Article Synopsis
- Protein-based therapeutics face challenges with delivery and site-specific action, but our approach involves covalently attaching these proteins to medical devices for targeted delivery.
- We studied the binding of glucagon-like peptide-2 (GLP-2) to vaginal and intestinal expansion sleeves, using chemically reactive surfaces to enable effective binding of this therapeutic agent.
- Our results showed that about 44% of the applied GLP-2 could be immobilized on the devices, allowing for lower doses to achieve similar therapeutic effects compared to traditional systemic administration, while minimizing side effects.
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