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From the archives of MD Anderson Cancer Center: EBV-positive fibrin-associated large B-cell lymphoma in an ovarian leiomyoma with cystic degeneration: A case report and discussion of differential diagnosis.
Ann Diagn Pathol
February 2025
Department of Anatomical Pathology, Division of Pathology and Laboratory Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA. Electronic address:
Article Synopsis
- Fibrin-associated large B-cell lymphoma (FA-LBCL) is a rare lymphoma linked to Epstein-Barr virus (EBV), as demonstrated in a case of a 53-year-old woman with a right ovarian mass.
- The patient presented with bloating and weight gain, leading to the discovery of a large cystic mass, which upon surgical examination revealed atypical lymphoid cells and was diagnosed as EBV-positive FA-LBCL.
- After receiving a standard chemotherapy regimen (R-CHOP), the patient showed no signs of disease and is currently in remission, highlighting the importance of recognizing and correctly diagnosing this uncommon lymphoma type.
Fibrin-associated diffuse large B-cell lymphoma in the aortic valve and ascending aorta.
J Cardiol Cases
September 2024
Department of Cardiovascular Surgery, Kanazawa University, 13-1 Takara-machi, Kanazawa 920-8641, Japan.
Unlabelled: Primary cardiac lymphoma is an extremely rare disease, with the most common being diffuse large B-cell lymphoma (DLBCL). Fibrin-associated diffuse large B-cell lymphoma (FA-DLBCL) has been classified as a rare and unusual type of lymphoma and is included in the category of DLBCL associated with chronic inflammation (DLBCL-CI). In this study, we report a case of FA-DLBCL in the aortic valve and ascending aorta of a 51-year-old-woman.
View Article and Find Full Text PDFFibrin associated large B-cell lymphoma accidentally identified in a breast implant capsule: a molecular report of a rare entity.
Pathologica
August 2024
Anatomic Pathology Unit, Department of Medical Biotechnology, University of Siena, Siena, Italy.
Breast implant-associated (BIA) lymphoma is a rare malignancy, typically originating from T-cells; however, few cases of diffuse large B-cell lymphoma (LBCL) have been recently described. These cases share major features: Epstein-Barr virus positivity and a favorable prognosis with surgical intervention alone, hinting at a potential link to fibrin-associated LBCL (FA-LBCL). This study presents the first case of BIA-FA-LBCL in Italy and one of the few assessed from a molecular standpoint so far.
View Article and Find Full Text PDFSplenic cyst deroofing complicated with B lymphoma.
World J Surg Oncol
September 2024
Department of Surgery, Faculty of Medicine, Unit of HPB Surgery and Abdominal Organ Transplantation, Complutense University, Madrid, Spain.
Background: Splenic cysts are uncommon and very rarely malignant therefore their treatment isn't standardized. In case of symptomatic cysts different surgical approaches have been suggested. Primary malignant lymphoma of the spleen comprises less than 1% of non-Hodgkin's lymphomas.
View Article and Find Full Text PDFFibrin-associated diffuse large B-cell lymphoma in a pediatric patient.
Pediatr Blood Cancer
September 2024
Department of Pediatrics, Hematology/Oncology Division, University of Illinois Chicago, Chicago, Illinois, USA.
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