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DPPX antibody-mediated disease mimicking Wernicke's encephalopathy.
BMJ Case Rep
January 2025
Neurology, Joondalup Health Campus, Joondalup, Western Australia, Australia.
Anti-dipeptidyl-peptidase-like protein 6 antibody-mediated disease is a rare autoimmune encephalitis typically presenting with diarrhoea and/or weight loss, central nervous system hyperexcitability and cognitive dysfunction. We present a case of a young woman with 10 days of diplopia and unsteadiness in the context of dysthymia and significant weight loss over 2 months. Initial examination demonstrated mixed dysconjugate nystagmus and ataxic gait.
View Article and Find Full Text PDFGlutamic Acid Decarboxylase 65 Antibody-associated Epilepsy and Diplopia: Two Case Reports with Literature Review.
Cerebellum
December 2024
Department of Neurology, the Fourth Affiliated Hospital of School of Medicine, and International School of Medicine, International Institutes of Medicine, Zhejiang University, Yiwu, 322000, China.
Glutamic acid decarboxylase 65 (GAD65) antibody-associated epilepsy and diplopia are relatively rare. This article retrospectively analyzed the disease development, diagnosis and treatment process of two cases of GAD65-associated epilepsy with diplopia. Both patients initially exhibited seizures, followed by the onset of diplopia and nystagmus.
View Article and Find Full Text PDFTraumatic bilateral internuclear ophthalmoplegia with plus syndrome.
BMJ Case Rep
November 2024
Ophthalmology, All India Institute of Medical Sciences, Nagpur, Maharashtra, India.
A young man in his 20s sustained head and body injuries after a fall from a height, 1 year ago for which he received emergency medical and surgical intervention. A month after the trauma, he noticed outward deviation of the right eye intermittently but did not experience diplopia. On examination, he had a bilateral adduction deficit, bilateral abduction nystagmus and a bilateral vertical nystagmus.
View Article and Find Full Text PDFWallenberg Syndrome Secondary to Vertebrobasilar Aneurysm Associated With Subclavian Steal Syndrome.
Cureus
October 2024
Department of Neuroscience, Instituto Nacional de Cancerología, Mexico City, MEX.
Wallenberg syndrome, also known as lateral medullary syndrome, is a rare condition affecting the vertebrobasilar circulation, causing symptoms such as vertigo, nystagmus, dysarthria, and hemifacial weakness. Typically linked to ischemic strokes, it can also arise from vertebrobasilar aneurysms. In rare cases, subclavian steal syndrome (SSS), involving retrograde flow in the vertebral artery due to subclavian stenosis, complicates the picture, as observed in this case of a 66-year-old woman with both conditions and a vertebrobasilar aneurysm.
View Article and Find Full Text PDFTraumatic Unilateral Internuclear Ophthalmoplegia in a 5-Year-Old Child.
J Pediatr Ophthalmol Strabismus
November 2024
The authors present the case of a 5-year-old boy who developed a unilateral internuclear ophthalmoplegia (INO) following mild head trauma with supporting magnetic resonance imaging (MRI) findings of damage to the medial longitudinal fasciculus. At 2 months of follow-up, the patient had resolution of diplopia and only minimal residual nystagmus. Although rare in the children, INO can develop following head trauma.
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