AI Article Synopsis
- The study aimed to assess how Behçet's syndrome (BS) impacts tear osmolarity and various tear film function tests in patients compared to healthy controls.
- Results showed that patients with BS had higher tear osmolarity and OSDI scores, while tests measuring tear film stability and production (like TBUT and Schirmer's test) were significantly lower.
- There was a notable link between higher tear osmolarity and increased OSDI scores, indicating that BS can lead to damage in the tear film and ocular surface.
Article Abstract
Objective: To evaluate the effects of Behçet's syndrome (BS) on tear osmolarity and tear film function tests.
Methods: Thirty patients with BS and 41 control subjects were enrolled in this study. Tear osmolarity was measured with an osmometer. Tear film function tests involved corneal fluorescein staining, tear film breakup time (TBUT), Schirmer's 1 test, and an Ocular Surface Disease Index (OSDI) Questionnaire.
Results: The patients with BS had significantly higher tear osmolarity (p = 0.000) and OSDI scores (p = 0.000) than the healthy controls. The TBUT (p = 0.000) and Schirmer's 1 test (p = 0.033) results were significantly lower in the BS group, but the fluorescein staining results were not statistically different. A significant correlation was found between tear osmolarity, OSDI, and the activity of BS.
Conclusions: BS is associated with hyperosmolarity of the tear film, which can damage the ocular surface and affect tear functions.
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| http://dx.doi.org/10.1016/j.jcjo.2018.03.008 | DOI Listing |
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