Background/aims: In the ABC classification system, group A consists of seronegative subjects without gastric corpus atrophy. This study aimed to determine the prevalence and characteristics of pseudo group A subjects.
Methods: Group A subjects were identified among consecutive Korean adults who underwent a serum anti- immunoglobulin G (IgG) test and pepsinogen (PG) assay on the day of endoscopy. Past infection was defined as the presence of either eradication history or endoscopic findings suggesting past infection (i.e., gastric xanthoma, metaplastic gastritis, or advanced atrophy >closed-type 1).
Results: Among 2,620 group A subjects, 448 (17.1%) had eradication history, and 133 (5.1%) showed endoscopic findings suggesting past infection. Older age (odds ratio [OR], 1.148; 95% confidence interval [CI], 1.067 to 1.236) and earlier year of birth (OR, 1.086; 95% CI, 1.009 to 1.168) were independent risk factors for classification into pseudo group A, with cutoff points at 50.5 years and birth year of 1959.5, respectively. Positive test findings were found in 22 subjects (3.1%) among the 715 subjects who underwent the urea breath test or Giemsa staining on the same day. Current infection was positively correlated with PG I and PG II levels (p<0.001) but not with age, anti- IgG titer, or classification into pseudo group A.
Conclusions: Among the group A subjects, 22.2% had past infection. The risk was higher in subjects older than 50 years, especially those born before 1960. Furthermore, current infection was found in 3.1% of the subjects and was correlated with increased gastric secretory ability.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6743811 | PMC |
| http://dx.doi.org/10.5009/gnl18399 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Genome Analysis of Coxsackievirus A4 Identified from Herpangina Children in Northern China.
Curr Microbiol
January 2025
Women and Children's Health Care Hospital of Linyi, No.1 Qinghe South Road, Luozhuang District, Linyi, Shandong, China.
Sporadic epidemics of coxsackievirus A4 (CVA4) have been reported worldwide. However, the lack of the whole genome sequence has restricted the study of the gene characterization and evolution of CVA4. In this study, four whole genome sequences and 17 VP1 sequences of CVA4 identified from Linyi, northern China, in summer 2024 were used for genetic characterization and phylogenetic analysis.
View Article and Find Full Text PDFPrediction of Deoxynivalenol contamination in wheat kernels and flour based on visible near-infrared spectroscopy, feature selection and machine learning modelling.
Spectrochim Acta A Mol Biomol Spectrosc
January 2025
Department of Environment, Faculty of Bioscience Engineering, Ghent University, 9000 Ghent, Belgium. Electronic address:
Contamination of wheat by the mycotoxin Deoxynivalenol (DON), produced by Fusarium fungi, poses significant challenges to the quality of crop yield and food safety. Visible and near-infrared (vis-NIR) spectroscopy has emerged as a promising, non-destructive, and efficient tool for detecting mycotoxins in cereal crops and foods. This study aims to utilize vis-NIR spectroscopy, coupled with a feature selection technique and machine learning modelling, to predict and classify DON contamination in wheat kernels and flour.
View Article and Find Full Text PDFGenome-Wide Identification and Expression Analysis of HSP70 Gene Family Under High-Temperature Stress in Lettuce ( L.).
Int J Mol Sci
December 2024
College of Plant Science and Technology, Beijing University of Agriculture, Beijing 102206, China.
The heat shock protein 70 (HSP70) family plays an important role in the growth and development of lettuce and in the defense response to high-temperature stress; however, its bioinformatics analysis in lettuce has been extremely limited. Genome-wide bioinformatics analysis methods such as chromosome location, phylogenetic relationships, gene structure, collinearity analysis, and promoter analysis were performed in the gene family, and the expression patterns in response to high-temperature stress were analyzed. The mechanism of in heat resistance in lettuce was studied by virus-induced gene silencing (VIGS) and transient overexpression techniques.
View Article and Find Full Text PDFEvaluation of Peri-Implantitis through Fourier-Transform Infrared Spectroscopy on Saliva.
J Proteome Res
January 2025
University of Santo Amaro (UNISA), Rua Isabel Schmidt 349, São Paulo 04743-030, Brazil.
Background: Peri-implantitis is characterized as a pathological change in the tissues around dental implants. Fourier-transform infrared spectroscopy (FTIR) provides molecular information from optical phenomena observed by the vibration of molecules, which is used in biological studies to characterize changes and serves as a form of diagnosis.
Aims: this case-control study evaluated the peri-implant disease by using FTIR spectroscopy with attenuated total reflectance in the fingerprint region.
Impact of trace metal supplementation on anaerobic biological methanation under hydrogen and carbon dioxide starvation.
NPJ Biofilms Microbiomes
January 2025
Department of Biology, University of Padua, via U. Bassi 58/b, 35131, Padova, Italy.
Biomethanation is a crucial process occurring in natural and engineered systems which can reduce carbon dioxide to methane impacting the global carbon cycle. However, little is known about the effect of on-and-off gaseous provision and micronutrients on bioconversion. Here, anaerobic microbiomes underwent intermittent feeding with incremental starvations and selective metal supplementation to assess the impact of hydrogen and carbon dioxide availability on microbial physiology.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!