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Talent Identification: Time to Move Forward on Estimation of Potentials? Proposed Explanations and Promising Methods.
Sports Med
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IRMES-UPR 7329, Institut de Recherche Médicale et d'Épidémiologie du Sport, Université Paris Cité, 11 Avenue du Tremblay, 75012, Paris, France.
The scientific literature on talent identification is extensive, with significant advancements made over the past 30 years. However, as with any field, the translation of research into practice and its impact on the field have been slower than anticipated. Indeed, recent findings highlight a pervasive relative age effect, the effects of maturation being often overlooked, disparate populations between young and senior performers, and a necessity to embrace a holistic approach.
View Article and Find Full Text PDFIntegration of Motion and Stillness: A Paradigm Shift in Constructing Nearly Planar NIR-II AIEgen with Ultrahigh Molar Absorptivity and Photothermal Effect for Multimodal Phototheranostics.
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Department of Chemistry, The Hong Kong Branch of Chinese National Engineering Research Center for Tissue Restoration and Reconstruction, Division of Life Science, State Key Laboratory of Molecular Neuroscience, and Department of Chemical & Biological Engineering, The Hong Kong University of Science and Technology, Clear Water Bay, Kowloon, Hong Kong 999077, China.
The two contradictory entities in nature often follow the principle of unity of opposites, leading to optimal overall performance. Particularly, aggregation-induced emission luminogens (AIEgens) with donor-acceptor (D-A) structures exhibit tunable optical properties and versatile functionalities, offering significant potential to revolutionize cancer treatment. However, trapped by low molar absorptivity (ε) owing to the distorted configurations, the ceilings of their photon-harvesting capability and the corresponding phototheranostic performance still fall short.
View Article and Find Full Text PDFExtending health equity to people with moderate and mild hemophilia A: revisiting the HAVEN 6 trial.
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Department of Pediatrics and Pathology, University of Michigan, Ann Arbor, Michigan, USA.
Congenital hemophilia A (HA) disease severity has traditionally been categorized according to intrinsic factor (F)VIII levels, with <1% of normal indicating severe HA, 1% to 5% moderate HA, and 6% to 40% mild HA. However, mounting evidence illustrates considerable variability in bleeding phenotype regardless of FVIII level. Despite treatment advances, people with moderate or mild HA may be neglected, as treatment guidelines and established norms focus on FVIII levels, and many clinical trials do not include people with FVIII > 1%.
View Article and Find Full Text PDFSingle-atom single-superatom as catalysts for ammonia production.
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Physics Department, Virginia Commonwealth University, Richmond, VA 23284, USA.
A new class of single-superatom catalyst (TiO, ZrO, and WC) supported on graphene is shown to outperform the stability and activity of their corresponding single-atom catalysts (Ni, Pd and Pt) for the electrochemical nitrogen reduction reaction. The results based on density functional theory point to a paradigm shift in catalyst design.
View Article and Find Full Text PDFWhen is synthetic sufficient? Ethical considerations and alternatives in simulation-based ultrasound education.
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RCSI SIM Centre for Simulation Education and Research, RCSI University of Medicine and Health Sciences, Dublin, Ireland.
Simulation-based education (SBE) has become an integral part of training in health professions education, offering a safe environment for learners to acquire and refine clinical skills. As a non-ionising imaging modality, ultrasound is a domain of health professions education that is particularly supported by SBE. Central to many simulation programs is the use of animal models, tissues, or body parts to replicate human anatomy and physiology.
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