The functionalization of polymeric substances is of great interest for the development of innovative materials for advanced applications. For many decades, the functionalization of chitosan has been a convenient way to improve its properties with the aim of preparing new materials with specialized characteristics. In the present review, we summarize the latest methods for the modification and derivatization of chitin and chitosan under experimental conditions, which allow a control over the macromolecular architecture. This is because an understanding of the interdependence between chemical structure and properties is an important condition for proposing innovative materials. New advances in methods and strategies of functionalization such as the click chemistry approach, copolymerization, coupling with cyclodextrins, and reactions in ionic liquids are discussed.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6414943 | PMC |
| http://dx.doi.org/10.3390/polym10030342 | DOI Listing |
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