We herein selected a 3D metal⁻organic framework decorated with carboxylate groups as an adsorbent to remove the pharmaceutical molecules of diclofenac sodium and chlorpromazine hydrochloride from water. The experiment aimed at exploring the effect factors of initial concentration, equilibrium time, temperature, pH and adsorbent dosage on the adsorption process. The adsorption uptake rate of the diclofenac sodium is much higher than that of the chlorpromazine hydrochloride. This paper presents the high adsorption capacity of diclofenac sodium, in which porous MOFs are used for the removal of drug contaminants from water. According to linear fitting with adsorption isotherm equation and kinetic equations, diclofenac sodium conforms to the Langmuir model and pseudo-first-order kinetic equation, while chlorpromazine hydrochloride accords with the Temkin model and pseudo-second-order kinetic equation. The results of the study indicate that the title compound could be a promising hybrid material for removing diclofenac sodium and chlorpromazine hydrochloride from wastewater.
Download full-text PDF |
Source |
---|---|
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6414845 | PMC |
http://dx.doi.org/10.3390/polym10020209 | DOI Listing |
Soft Matter
January 2025
Department of Chemistry and Chemical Biology, Indian Institute of Technology (ISM), Dhanbad-826004, India.
Drug delivery vehicles optimize therapeutic outcomes by enhancing drug efficacy, minimizing side effects, and providing controlled release. Injectable hydrogels supersede conventional ones in the field of drug delivery owing to their less invasive administration and improved targeting. However, they face challenges such as low biodegradability and biocompatibility, potentially compromising their effectiveness.
View Article and Find Full Text PDFACS Omega
January 2025
Department of Chemistry, Banaras Hindu University, Varanasi, Uttar Pradesh 221005, India.
The ZrO-embedded carboxy-functionalized -BN composite, combined with graphene oxide (GO), formed a novel BN-COOH@ZrO/GO composite. Structural characterization through IR, Raman spectroscopy, powder X-ray diffraction, and X-ray photoelectron spectroscopy supported the successful preparation of the composite, while scanning electron microscopy and transmission electron microscopy revealed its surface morphology and the presence of component materials. UV-vis spectroscopy (solid state) further supported these findings.
View Article and Find Full Text PDFFood Chem Toxicol
January 2025
UCB, 216 Bath Road, Slough SL1 3WE, United Kingdom. Electronic address:
The use of cannabis-related products is currently experiencing extraordinary growth in popularity in the European and US markets. A wide variety of cannabis-related products have emerged, including oils, tinctures, edibles, topicals, cosmetics, and even beverages and sweets, offering the purported medical benefits without the psychoactive effects associated with Cannabis sativa. However, there is a significant gap in our understanding of bioaccumulation processes and their long-term effects, particularly as cannabinoids are highly lipophilic molecules.
View Article and Find Full Text PDFSci Total Environ
January 2025
Federal University of Santa Catarina, Agricultural Sciences Center, Department of Food Science and Technology, Brazil. Electronic address:
This study aimed to implement a targeted multiple reaction monitoring (MRM) screening strategy using liquid chromatography coupled with tandem mass spectrometry (LC-MS/MS) for the initial detection of 165 compounds of emerging concern (CECs) in water, sediment, and fish samples. Following the screening, confirmatory and quantitative analyses were conducted using analytical standards for the detected compounds. Qualitative results were confirmed using high-resolution mass spectrometry (HRMS) for those CECs without available standards.
View Article and Find Full Text PDFNat Prod Res
January 2025
Department of Applied Science, Faculty of Engineering & Technology, Gurukula Kangri (Deemed to be University), Haridwar, India.
The present study aimed to evaluate the nutrition value, phytochemical content, and diverse pharmacological activities of different solvent extracts of L. fruit. Among all, the hydro-alcoholic extract showed high DPPH and ABTS radical scavenging activities with IC values of 82.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!