Background: Heart failure (HF) is classified in three class: HF with preserved EF (HFpEF); normal or LVEF ≥ 50%, HF with reduced EF (HFrEF); LEVF < 40% and newly HF mid-range EF (HFmrEF); LVEF 40-49%. On Electrocardiography (ECG) T wave, Tpeak-Tend (Tp-Te) interval reflects transmural dispersion of repolarisation (TDR) which of these indexes have been proposed as predictors of risk for ventricular arrhythmia (VA) in many cardiac diseases.
Aim: Aim of this study to asses these indices of TDR among three HF class.
Methods: Total of 192 patients were included in this study.
Results: Many of indices like Tp-Te, Tp-Te/QT wasn't different between groups (P > 0.05). But mean Q-Tpeak (QTp), S-Tend (S-Te) and S-Tpeak (S-Tp) were found significantly different between groups (P < 0.05). Again S-Te was found different according to having fragmented QRS (fQRS) on ECG (P = 0.031). Comparing to mitral inflow E/A parameters showed significant differences for Tp-Te, Tp-Tec, Tp-Te/QT, Tp-Te/QTc and Tp-Tec/QTc parameters. Finally, we found correlations between S-Te and white blood cell (WBC) (r = - 0.171; P = 0.037) and S-Tp and WBC (r = - 0.170; P = 0.038) and between S-Te and fQRS (r = 0.158; P = 0.031).
Conclusions: We didn't find differences for many of indices of TDR like Tp-Te interval between groups except QTp, S-Te, S-Tp intervals. Also, S-Te and fQRS showed significant correlation. For prediction of ventricular arrhythmia and cardiovascular death newer indexes on ECG are needed to be established in the future which will make us facilitate to distinguish high risk patients.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6447328 | PMC |
| http://dx.doi.org/10.3889/oamjms.2019.186 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Immediate changes in depolarization and repolarization after left bundle branch area pacing and atrioventricular nodal ablation.
J Electrocardiol
November 2024
Hacettepe University, Faculty of Medicine, Department of Cardiology, Ankara, Turkey.
Background: Malignant arrhythmia due to ventricular depolarization and repolarization alterations after atrioventricular node (AVN) ablation is a known clinical entity. Here, we aimed to demonstrate the ventricular depolarization and repolarization changes in patients who underwent left bundle branch area pacing (LBBaP) and AVN ablation.
Methods: This is a single-center, retrospective preliminary study (n = 10).
Predictive value of Tpeak-Tend interval of supine and orthostatic electrocardiogram in the diagnosis between psychogenic pseudosyncope and vasovagal syncope in children.
Sci Rep
November 2024
Department of Pediatric Cardiovasology, Children's Medical Center, The Second Xiangya Hospital, Central South University, No.139 Renmin Middle Road, Changsha, 410011, Hunan, China.
Article Synopsis
- - The study investigates the Tpeak-Tend interval (Tp-Te) as a diagnostic tool for distinguishing between psychogenic pseudosyncope (PPS) and vasovagal syncope (VVS) in children, examining data from 31 children with PPS and 40 with VVS.
- - Results demonstrate that the Tp-Te and its ratio to the QT interval are significantly lower in PPS compared to healthy controls, while VVS patients show higher Tp-Te values in certain ECG leads compared to controls.
- - In orthostatic ECG tests, the PPS group exhibited higher Tp-Te measures relative to healthy controls, indicating potential differences in repolarization patterns that could help differentiate between PPS and VVS in pediatric
The assessment of adolescent obesity's effects on ventricular repolarization.
J Electrocardiol
September 2024
Department of Paediatric Endocrinology, Selcuk University, Faculty of Medicine, Konya, Turkey.
Background: Currently, there is a lack of research on the Tp-Te interval and Tp-e/QT ratio in obese adolescents who have metabolic syndrome.
Aim: Our study aims to compare established ventricular repolarization parameters with these intervals and ratios in obese adolescents with or without metabolic syndrome, alongside a healthy control group, while exploring the association of these repolarization parameters with cardiovascular risk factors and echocardiographic variables.
Methods: The study included 100 obese adolescents and 50 lean subjects, with the obese participants categorized into two subgroups.
Assessment of Tp-Te interval in patients with cardiac AL amyloidosis.
Cardiovasc J Afr
January 2024
Department of Internal Medicine, Istanbul University, Istanbul Faculty of Medicine, Istanbul, Turkey.
Background: Prolonged Tp-Te interval is strongly associated with fatal ventricular arrhythmias and mortality. This association has been demonstrated in various diseases. However, the current literature does not give any information on Tp-Te interval in cardiac amyloid light-chain (AL) amyloidosis.
View Article and Find Full Text PDFImprovement in electrocardiographic parameters of repolarization related to sudden death in patients with ventricular dysfunction and left bundle branch block after cardiac resynchronization through His bundle pacing.
J Interv Card Electrophysiol
December 2023
Department of Cardiology, HJRJ, Ronda Norte S/N., Huelva, Spain.
Background: Cardiac resynchronization therapy (CRT) through permanent His bundle pacing (p-HBP) normalizes interventricular conduction disorders and QRS. Similarly, there are immediate and long-term changes in repolarization, which could be prognostic of a lower risk of sudden death (SD) at follow-up. We aimed to compare the changes in different electrocardiographic (ECG) repolarization parameters related to the risk of SD before and after CRT through p-HBP.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!