Synthetic Aperture RADAR (SAR) is a radar imaging technique in which the relative motion of the sensor is used to synthesize a very long antenna and obtain high spatial resolution. Several algorithms for SAR data-focusing are well established and used by space agencies. Such algorithms are model-based, i.e., the radiometric and geometric information about the specific sensor must be well known, together with the ancillary data information acquired on board the platform. In the development of low-cost and lightweight SAR sensors, to be used in several application fields, the precise mission parameters and the knowledge of all the specific geometric and radiometric information about the sensor might complicate the hardware and software requirements. Despite SAR data processing being a well-established imaging technique, the proposed algorithm aims to exploit the SAR coherent illumination, demonstrating the possibility of extracting the reference functions, both in range and azimuth directions, when a strong point scatterer (either natural or manmade) is present in the scene. The Singular Value Decomposition is used to exploit the inherent redundancy present in the raw data matrix, and phase unwrapping and polynomial fitting are used to reconstruct clean versions of the reference functions. Fairly focused images on both synthetic and real raw data matrices without the knowledge of mission parameters and ancillary data information can be obtained; as a byproduct, azimuth beam pattern and estimates of a few other parameters have been extracted from the raw data itself. In a previous paper, authors introduced a preliminary work dealing with this problem and able to obtain good-quality images, if compared to the standard processing techniques. In this work, the proposed technique is described, and performance parameters are extracted to compare the proposed approach to RD, showing good adherence of the focused images and pulse responses.
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http://dx.doi.org/10.3390/s19071649 | DOI Listing |
Elife
January 2025
Integrative Model-Based Cognitive Neuroscience Research Unit, University of Amsterdam, Amsterdam, Netherlands.
This study investigates the functional network underlying response inhibition in the human brain, particularly the role of the basal ganglia in successful action cancellation. Functional magnetic resonance imaging (fMRI) approaches have frequently used the stop-signal task to examine this network. We merge five such datasets, using a novel aggregatory method allowing the unification of raw fMRI data across sites.
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Student Research Committee, Department of Community Nutrition, Faculty of Nutrition Sciences and Food Technology, National Nutrition and Food Technology Research Institute, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
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Digit Health
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School of Computer Science, The University of Sydney, Sydney, NSW, Australia.
Objective: Machine learning (ML) has enabled healthcare discoveries by facilitating efficient modeling, such as for cancer screening. Unlike clinical trials, real-world data used in ML are often gathered for multiple purposes, leading to bias and missing information for a specific classification task. This challenge is especially pronounced in healthcare because of stringent ethical considerations and resource constraints.
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Department of Oncology, Georgetown University Medical Center, Washington, DC, United States.
Cancer's epigenetic landscape, a labyrinthine tapestry of molecular modifications, has long captivated researchers with its profound influence on gene expression and cellular fate. This review discusses the intricate mechanisms underlying cancer epigenetics, unraveling the complex interplay between DNA methylation, histone modifications, chromatin remodeling, and non-coding RNAs. We navigate through the tumultuous seas of epigenetic dysregulation, exploring how these processes conspire to silence tumor suppressors and unleash oncogenic potential.
View Article and Find Full Text PDFJ Toxicol Pathol
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Department of Molecular Pathology, Graduate School of Medicine, Osaka Metropolitan University, 1-4-3 Asahi-machi, Abeno-ku, Osaka, Japan.
Occupational exposure to aromatic amines is a major risk factor for urinary bladder cancer. Our previous studies showed that acetoaceto--toluidine, which is produced using -toluidine as a raw material, promotes urinary bladder carcinogenesis in rats. We also found high concentrations of -toluidine, a human bladder carcinogen, in the urine of acetoaceto--toluidine-treated rats, indicating that urinary -toluidine derived from acetoaceto--toluidine may play an important role in bladder carcinogenesis.
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