AI Article Synopsis
- Sarcoidosis is a global disease characterized by the formation of granulomas, primarily affecting the lungs but also potentially involving any organ.
- Diagnosis relies on clinical signs, pathology, and ruling out other granulomatous diseases.
- Treatment typically involves immunosuppressive therapy, especially for symptomatic or progressive cases, or when critical organs like the eyes, heart, or nervous system are affected.
Article Abstract
Sarcoidosis is a multisystemic granulomatous disease that affects individuals worldwide. The lungs are most commonly involved but any organ can be involved. It has variable manifestations and clinical course. Diagnosis of sarcoidosis is based on clinicopathologic findings and the exclusion of other causes of granulomatous disease. Its hallmark is the formation of granulomas in affected organs. Immunosuppressive therapy is the cornerstone of the management of sarcoidosis and is indicated when there is evidence of symptomatic or progressive disease or when critical organs (ocular, cardiac, nervous system) are involved.
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| http://dx.doi.org/10.1016/j.mcna.2018.12.011 | DOI Listing |
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