In this experimental study, we did peripheral neurectomyand peripheral cryoneurotomy of the mental nerve in rats and histologically assessed their effects on the trigeminal ganglion at timed intervals for six months. There were marked irreversible changes in the neurectomy group whereas the cryoneurotomy group made a full recovery. These results help to explain the differing effects of these procedures on trigeminal neuralgia.
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Cryoneurotomy in the management of intractable trigeminal neuralgia.
Br J Oral Maxillofac Surg
November 2020
Oral & Maxillofacial Surgery Unit, The University of Adelaide, South Australia; Department of Oral and Maxillofacial Surgery, Faculty of Medicine, Saitama Medical University, Saitama, Japan.
In this paper we describe the effects of peripheral cryoneurotomy on a consecutive series of patients with intractable trigeminal neuralgia (TN) who had been treated by a single surgeon over a ten-year period. The results of 55 patients who underwent a total of 102 cryoneurotomies were documented. The age at first cryofreeze was 64 (30-92) years with 24 males and 31 females.
View Article and Find Full Text PDFEffect of peripheral cryoneurotomy and nerve transection on the trigeminal ganglion in rats.
Br J Oral Maxillofac Surg
May 2019
Oral & Maxillofacial Surgery, The University of Adelaide, Adelaide, Australia. Electronic address:
In this experimental study, we did peripheral neurectomyand peripheral cryoneurotomy of the mental nerve in rats and histologically assessed their effects on the trigeminal ganglion at timed intervals for six months. There were marked irreversible changes in the neurectomy group whereas the cryoneurotomy group made a full recovery. These results help to explain the differing effects of these procedures on trigeminal neuralgia.
View Article and Find Full Text PDF[Potential limitations and risks in the treatment of painful neuropathies].
Schmerz
August 2000
Neurochirurgische Klinik, Friederikenstift Hannover.
Introduction: Neuropathic pains often cause social disintegration of the patients, encouraging us to apply microsurgical techniques to peripheral nerve lesions, but there are limitations and risks to take into account when handling scarred nerve tissue.
Facts And Theoretical Considerations: The historical development of our microanatomical knowledge of grading of nerve lesions as well as facts on different fibrotic intraneural reactions are pointed out and additionally compared to today's theories of the origin of neuropathic pains.
Methods: The microsurgical methods applied to entrapment syndromes, pseudoneuroma and neuroma formations consist of either external and interfascicular neurolysis or nerve grafting depending on the estimated grade of nerve lesion.
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