Platelets Give a Running Start to Adult Hippocampal Neurogenesis.

Stem Cell Reports

Department of Anatomy, University of California San Francisco, San Francisco, CA, USA; Biomedical Sciences Graduate Program, University of California San Francisco, San Francisco, CA, USA; Department of Physical Therapy and Rehabilitation Science, San Francisco, CA, USA; The Eli and Edythe Broad Center for Regeneration Medicine and Stem Cell Research, San Francisco, CA, USA. Electronic address:

Published: April 2019

Exercise boosts neural stem and progenitor cell proliferation and differentiation in the dentate gyrus region of the hippocampus. In this issue of Stem Cell Reports, Leiter et al. (2019) identify acute exercise-induced platelet activation and platelet factor-4 as novel systemic mediators of adult hippocampal neurogenesis.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6450820PMC
http://dx.doi.org/10.1016/j.stemcr.2019.03.007DOI Listing

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