Objectives: When younger adults simulated positive future events, subsequent memory is positively biased. In the current studies, we explore age-related changes in the impact of emotional future simulation on subsequent memory.
Methods: In Experiment 1, younger and older adults simulated emotional future events before learning the hypothetical outcome of each event via narratives. Memory was assessed for emotional details contained in those narratives. In Experiment 2, a shorter temporal delay between simulation and narrative encoding was used to reduce decay of simulation memory over time.
Results: Future simulation did not bias subsequent memory for older adults in Experiment 1. However, older adults performed similar to younger adults in Experiment 2, with more liberal responses to positive information after positive simulation.
Discussion: The impact of an optimistic outlook on subsequent memory is reduced with age, which may be at least partly attributable to declining memory for future simulations over time. This work broadens our understanding of the functional consequences of age-related declines in episodic future simulation and adds to previous work showing reduced benefits of simulation with age on tasks tapping adaptive functions.
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http://dx.doi.org/10.1093/geronb/gbz041 | DOI Listing |
Stem Cell Res Ther
January 2025
Organoid Innovation Center, Suzhou Institute of Nanotech and Nano-bionics, Chinese Academy of Sciences, 398 Ruoshui Rd, Suzhou, Jiangsu, 215123, China.
The lack of in vivo accurate human liver models hinders the investigation of liver-related diseases, injuries, and drug-related toxicity, posing challenges for both basic research and clinical applications. Traditional cellular and animal models, while widely used, have significant limitations in replicating the liver's complex responses to various stressors. Liver organoids derived from human pluripotent stem cells, adult stem cells primary cells, or tissues can mimic diverse liver cell types, major physiological functions, and architectural features.
View Article and Find Full Text PDFJ Clin Ultrasound
January 2025
JD Hamilton Consulting, Brighton, Michigan, USA.
Background: Ultrasound lung surface motion measurement is valuable for the evaluation of a variety of diseases. Speckle tracking or Doppler-based techniques are limited by the loss of visualization as a tracked point moves under ribs or is dependent.
Methods: We developed a synthetic lateral phase-based algorithm for tracking lung motion to overcome these limitations.
Nat Commun
January 2025
Department of Water and Climate, Vrije Universiteit Brussel, Brussels, Belgium.
Irrigation rapidly expanded during the 20 century, affecting climate via water, energy, and biogeochemical changes. Previous assessments of these effects predominantly relied on a single Earth System Model, and therefore suffered from structural model uncertainties. Here we quantify the impacts of historical irrigation expansion on climate by analysing simulation results from six Earth system models participating in the Irrigation Model Intercomparison Project (IRRMIP).
View Article and Find Full Text PDFNat Commun
January 2025
Laboratoire des Sciences du Climat et de l' Environnement, LSCE/IPSL, CEA-CNRS-UVSQ, Université Paris-Saclay, Gif-sur-Yvette, France.
Organic carbon burial (OCB) in lakes, a critical component of the global carbon cycle, surpasses that in oceans, yet its response to global warming and associated feedbacks remains poorly understood. Using a well-dated biomarker sequence from the southern Tibetan Plateau and a comprehensive analysis of Holocene total organic carbon variations in lakes across the region, here we demonstrate that lake OCB significantly declined throughout the Holocene, closely linked to changes in temperature seasonality. Process-based land surface model simulations clarified the key impact of temperature seasonality on OCB in lakes: increased seasonality in the early Holocene saw warmer summers enhancing ecosystem productivity and organic matter deposition, while cooler winters improved organic matter preservation.
View Article and Find Full Text PDFLife Sci Space Res (Amst)
February 2025
Division of Radiation Health, Department of Pharmaceutical Sciences, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA.
Future long duration space missions will expose astronauts to higher doses of galactic cosmic radiation (GCR) than those experienced on the international space station. Recent studies have demonstrated astronauts may be at risk for cardiovascular complications due to increased radiation exposure and fluid shift from microgravity. However, there is a lack of direct evidence on how the cardiovascular system is affected by GCR and microgravity since no astronauts have been exposed to exploratory mission relevant GCR doses.
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