The endocrine system is a complex interconnected system of organs that control corporeal processes and function. Primary endocrine organs are involved in hormonal production and secretion but rely on a bevy of signals from the hypothalamic-pituitary axis and secondary endocrine organs, such as the liver. In turn, proper hepatic function is maintained through hormonal signaling. Thus, the endocrine system and liver are codependent, and diseases affecting either organs can lead to alterations in function within their counterparts. This article explores the hepato-endocrine relationship, including the effects on endocrine diseases on the liver.
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| http://dx.doi.org/10.1016/j.cld.2018.12.006 | DOI Listing |
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Effects of a 12-week lower limb resistance training with breathing regulation in patients with diabetes-related foot ulcers: A randomized controlled trial.
Appl Nurs Res
April 2025
School of Nursing, National Taipei University of Nursing and Health Sciences, 365 Minte Road, Peitou District, Taipei 1112, Taiwan. Electronic address:
Patients with diabetes-related foot ulcers may require hospitalization and face an increased risk of amputation, which can significantly impact their quality of life. One potential solution is exercise, which can regulate blood glucose levels, improve wound healing, and enhance overall well-being. This randomized controlled trial aimed to evaluate the impact of a lower limb resistance training program combined with breathing-regulation techniques on glycemic control, wound healing, and quality of life in patients with diabetes-related foot ulcers.
View Article and Find Full Text PDFEffects of e-health literacy on health-related quality of life in young adults with type 2 diabetes: Parallel mediation of diabetes self-efficacy and self-care behaviors.
Appl Nurs Res
April 2025
College of Nursing, Research Institute of Nursing Science, Jeonbuk National University; Biomedical Research Institute, Jeonbuk National University Hospital, Jeonju, Republic of Korea. Electronic address:
Aim: To explore the impact of e-health literacy (e-HL) on health-related quality of life (HRQOL) in young adults with type 2 diabetes (T2D), focusing on the mediating roles of diabetes self-efficacy and self-care behaviors.
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Methods: The participants were 150 young adults, aged 18 to 39, with T2D.
Hypoglycemia knowledge assessment tool - Development and validation of the Hypoglycemia Management Knowledge Scale in Taiwan.
Appl Nurs Res
April 2025
Jing-Pin Clinic, No. 16, Shiquan 1st Rd., Kaohsiung City 807, Taiwan. Electronic address:
Background: Knowledge can guide and support behaviors. With accurate knowledge, patients are better equipped to engage in appropriate self-care behaviors and effectively manage hypoglycemia. However, there is currently a lack of reliable and valid assessment scales specifically designed to measure hypoglycemia knowledge, which could serve as valuable clinical evaluation tools for healthcare professionals.
View Article and Find Full Text PDFDiabetes-Related Extremity Amputation Depression and Distress (DREADD): A Multimethod Study.
Semin Vasc Surg
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Keck School of Medicine of USC, Los Angeles, CA.
Of the roughly 38 million people diagnosed with type 2 diabetes mellitus in the United States, up to 34% will develop a diabetic foot ulcer at some point, up to 75% of those who develop an ulcer will experience recurrent ulcers, and approximately 18% of patients with a diabetic foot ulcer will undergo lower-limb amputation. The aim of this study was to determine whether depressive symptoms change after a minor, nontraumatic amputation. We conducted a multimethod study consisting of semi-structured interviews (n = 12) and a retrospective cohort (n = 20) of patients with type 2 diabetes mellitus who underwent a nontraumatic, minor amputation of a single toe (partial or total) or partial ray resection.
View Article and Find Full Text PDFDiabetic foot infections: Questions for an infectious disease consultant.
Semin Vasc Surg
March 2025
Division of Infectious Disease, Department of Internal Medicine, University of Pittsburgh Medical Center, Pittsburgh, PA.
Diabetic foot infection can lead to limb amputation in approximately 17% of affected patients. Given the complex pathophysiology associated with diabetic foot infection, the goal of limb preservation is best achieved with a multidisciplinary approach and a team of providers including infectious disease consultants. However, these infections often affect populations living in nonmetropolitan areas, where access to an infectious disease physician may be limited.
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