We provide a detailed description of a serial femtosecond crystallography (SFX) dataset collected at the European X-ray free-electron laser facility (EuXFEL). The EuXFEL is the first high repetition rate XFEL delivering MHz X-ray pulse trains at 10 Hz. The short spacing (<1 µs) between pulses requires fast flowing microjets for sample injection and high frame rate detectors. A data set was recorded of a microcrystalline mixture of at least three different jack bean proteins (urease, concanavalin A, concanavalin B). A one megapixel Adaptive Gain Integrating Pixel Detector (AGIPD) was used which has not only a high frame rate but also a large dynamic range. This dataset is publicly available through the Coherent X-ray Imaging Data Bank (CXIDB) as a resource for algorithm development and for data analysis training for prospective XFEL users.
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http://dx.doi.org/10.1038/s41597-019-0010-0 | DOI Listing |
Sensors (Basel)
December 2024
Faculty of Engineering Science, University of Bayreuth, 95440 Bayreuth, Germany.
Molding sand mixtures in the foundry industry are typically composed of fresh and reclaimed sands, water, and additives such as bentonite. Optimizing the control of these mixtures and the recycling of used sand after casting requires an efficient in-line monitoring method, which is currently unavailable. This study explores the potential of an AI-enhanced electrical impedance spectroscopy (EIS) system as a solution.
View Article and Find Full Text PDFMaterials (Basel)
December 2024
Department of Mechanical Engineering, North Carolina A & T State University,1601 E. Market Street, Greensboro, NC 27411, USA.
Damage in composite laminates evolves through complex interactions of different failure modes, influenced by load type, environment, and initial damage, such as from transverse impact. This paper investigates damage growth in cross-ply polymeric matrix laminates under tensile load, focusing on three primary failure modes: transverse matrix cracks, delaminations, and fiber breaks in the primary loadbearing 0-degree laminae. Acoustic emission (AE) techniques can monitor and quantify damage in real time, provided the signals from these failure modes can be distinguished.
View Article and Find Full Text PDFJ Clin Med
December 2024
Department of Biomedical Informatics and Artificial Intelligence, Silesian University of Technology, 41-800 Zabrze, Poland.
Actinic keratoses (AK) usually occur on sun-exposed areas in elderly patients with Fitzpatrick I-II skin types. Dermatoscopy and ultrasonography are two non-invasive tools helpful in examining clinically suspicious lesions. This study presents the usefulness of image-processing algorithms in AK staging based on dermatoscopic and ultrasonographic images.
View Article and Find Full Text PDFBioengineering (Basel)
November 2024
Department of Mechanical Engineering, Korea Advanced Institute of Science and Technology (KAIST), Daejeon 34141, Republic of Korea.
Exosomes are extracellular nanovesicles secreted by cells that efficiently deliver therapeutic cargo for cancer treatment. However, because exosomes are present in low quantities and have limited target specificity, internal and external stress stimulation has been studied to increase exosome efficiency. Inspired by these studies, the uptake efficiency of cobalt chloride-induced hypoxic cancer cell-secreted exosomes was evaluated.
View Article and Find Full Text PDFPhys Eng Sci Med
January 2025
RF Longevity, 428 E. Thunderbird Road, Phoenix, SE, AZ, 85022, USA.
We have previously shown in small studies that full brain Transcranial Radiofrequency Wave Treatment (TRFT) to subjects with Alzheimer's Disease could stop and reverse their cognitive decline. An 8-emitter head device, the "MemorEM", was used in these studies to provide TRFT at 915 MHz frequency and power level of 1.6 W/kg Specific Absorption Rate (SAR) during daily 1-hour treatments.
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