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Correction to: Response to Juberg et al.
Environ Health
July 2020
Department of Public Health, University of Southern Denmark, Odense, Denmark.
An amendment to this paper has been published and can be accessed via the original article.
View Article and Find Full Text PDFEffect of GenX on P-Glycoprotein, Breast Cancer Resistance Protein, and Multidrug Resistance-Associated Protein 2 at the Blood-Brain Barrier.
Environ Health Perspect
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Laboratory of Toxicology and Toxicokinetics, National Cancer Institute at National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina, USA.
Background: Ammonium 2,3,3,3-tetrafluoro-2-(heptafluoropropoxy)propanoic acid (GenX) is a replacement for perfluorooctanoic acid in the production of fluoropolymers used in a variety of consumer products. GenX alters fetal development and antibody production and elicits toxic responses in the livers and kidneys of rodents. The GenX effect on the blood-brain barrier (BBB) is unknown.
View Article and Find Full Text PDFResponse to Juberg et al.
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Department of Public Health, University of Southern Denmark, Odense, Denmark.
Letter to the editor regarding "safety of safety evaluation of pesticides: developmental neurotoxicity of chlorpyrifos and chlorpyrifos-methyl" by Mie et al. (environmental health. 2018. 17:77).
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Charles River Laboratories, Ashland, OH, USA.
No treatment-related effects with aryloxyalkanoate dioxygenase-12 in three 28-day mouse toxicity studies.
Regul Toxicol Pharmacol
February 2018
Dow AgroSciences LLC., 9330 Zionsville Road, Indianapolis, IN 46268, USA. Electronic address:
The aryloxyalkanoate dioxygenase-12 (AAD-12) protein is expressed in genetically modified soybean events DAS-68416-4 and DAS-444Ø6-6. Expression of the AAD-12 protein in soybeans confers tolerance to the herbicide 2,4-dichlorophenoxyacetic acid (2,4-D) providing an additional herbicide choice to farmers. This enzyme acts by catalyzing the degradation of 2,4-D into herbicidally inactive metabolites.
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