Purpose: This research was designed to analyze the clinicopathological factors affecting the prognosis of cervical cancer.
Methods: The clinical and follow-up data of 79 patients with cervical cancer were retrospectively analyzed by univariate and multivariate analysis. The 5-year overall survival rate was 74% for all patients.
Results: Univariate analysis showed that the 5-year survival rate of patients with clinical stage I-IIA cervical cancer was higher than that of IIB-IV. The 5-year survival rates were higher in patients without parametrial invasion than those with parametrial invasion; higher in patients without vascular invasion than those with vascular invasion; and higher in patients without lymph node metastasis than those with lymph node metastasis. Multivariate analysis showed that vascular invasion, lymph node metastasis, and clinical stage were independent predictors of overall survival.
Conclusion: Vascular invasion, lymph node metastasis, and clinical stage are independent predictors for the prognosis of cervical cancer.
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BJOG
January 2025
Center for Research in Primary Health Care (CINAPS), Universidad Peruana Cayetano Heredia, Lima, Peru.
Iran J Med Sci
December 2024
Department of Urology, Hasheminejad Kidney Center, Iran University of Medical Sciences, Tehran, Iran.
Background: Labial adhesion (LA) is a total or partial labial fusion mostly seen in pre-pubertal children and is rare in premenopausal and postmenopausal periods. This review aimed to evaluate risk factors for labial fusion and the recurrence rate following surgical intervention in postmenopausal women.
Methods: According to PRISMA guidelines, international databases including Embase, World Cat, Web of Science, Scopus, Dimension, Open Grey, Cochrane, Google Scholar, and also PubMed gateway for PMC and MEDLINE were searched.
Front Surg
January 2025
Research Unit of Gynaecology, Department of Medicine and Surgery, Università Campus Bio-Medico di Roma, Rome, Italy.
Front Immunol
January 2025
The Third Affiliated Hospital of Beijing University of Chinese Medicine, Beijing University of Chinese Medicine, Beijing, China.
Background: Cervical cancer is the fourth most common cancer in women globally, and the main cause of the disease has been found to be ongoing HPV infection. Cervical cancer remains the primary cause of cancer-related death despite major improvements in screening and treatment approaches, especially in low- and middle-income nations. Therefore, it is crucial to investigate the tumor microenvironment in advanced cervical cancer in order to identify possible treatment targets.
View Article and Find Full Text PDFFront Oncol
January 2025
AO Vector-Best, Novosibirsk, Russia.
Background: Cervical screening, aimed at detecting precancerous lesions and preventing cancer, is based on cytology and HPV testing. Both methods have limitations, the main ones being the variable diagnostic sensitivity of cytology and the moderate specificity of HPV testing. Various molecular biomarkers are proposed in recent years to improve cervical cancer management, including a number of mRNAs encoded by human genes involved in carcinogenesis.
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