Polymeric Nanowires for Diagnostic Applications.

Micromachines (Basel)

Department of Chemical Engineering, Delft University of Technology, Van der Maasweg 9, 2629HZ Delft, The Netherlands.

Published: March 2019

Polymer nanowire-related research has shown considerable progress over the last decade. The wide variety of materials and the multitude of well-established chemical modifications have made polymer nanowires interesting as a functional part of a diagnostic biosensing device. This review provides an overview of relevant publications addressing the needs for a nanowire-based sensor for biomolecules. Working our way towards the detection methods itself, we review different nanowire fabrication methods and materials. Especially for an electrical signal read-out, the nanowire should persist in a single-wire configuration with well-defined positioning. Thus, the possibility of the alignment of nanowires is discussed. While some fabrication methods immanently yield an aligned single wire, other methods result in disordered structures and have to be manipulated into the desired configuration.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6523414PMC
http://dx.doi.org/10.3390/mi10040225DOI Listing

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