Background: The role of exercise stress echocardiography (ESE) in the pediatric population is less well defined as compared to adults. We aimed to determine the utility and impact of ESE on clinical decision-making in pediatric patients.
Methods: We identified patients who underwent an ESE at our center from 2011 to 2015. Test indications were categorized into symptoms with exercise; sports/activity clearance; hypertrophic cardiomyopathy (HCM) or suspected HCM; coronary anomalies; or abnormal electrocardiogram (EKG). Change in clinical management was assessed by comparing pre- and post-test activity restrictions, which were categorized into unrestricted from exercise or activity; restricted from exercise or activity; and surgical referral.
Results: During the study period, 353 ESEs met inclusion criteria. Of all ESEs performed, 263 (75%) were normal. Clinical management changed as a result of ESE in 144 (40%). Of the abnormal ESEs, 44 were restricted from activity, including 25 (56.8%) restricted from competitive or varsity athletics, 14 (31.8%) restricted from recreational sports, and 5 (11.4%) restricted from all activity. Surgical referrals included valve repair/replacement in 7 (50%), ICD placement in 5 (35.8%), coronary re-implantation in 1 (7.1%), and atrial septal defect repair in 1 (7.1%).
Conclusion: Exercise stress echocardiography provides the pediatric cardiologist with useful information that impacts management in a wide variety of cardiac disorders. Clinical management changed in nearly half the patients that were subjected to an ESE at our center. This supports the value of ESE for informing clinical decision-making. Future studies should aim to refine patient selection and examine its impact on patient outcomes.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1111/echo.14326 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Diagnostic Accuracy of Low-Dose Myocardial Perfusion Imaging in a Real-World Setting.
J Nucl Cardiol
January 2025
Université de Lorraine, CHRU-Nancy, Department of Nuclear Medicine and Nancyclotep Imaging Platform, F-54000, Nancy, France; Université de Lorraine, INSERM U1254, IADI, F-54000 Nancy, France. Electronic address:
Background: This large-scale study analyzes factors affecting diagnostic accuracy of low-dose myocardial perfusion imaging and correlation with coronary angiography in a real-world practice.
Methods: We compared data extracted from routine reports of (i) low-dose [Tc]sestamibi stress-MPI performed with no attenuation correction and predominantly exercise stress testing and (ii) the corresponding coronary angiography.
Results: We considered 1070 pairs of coronary angiography/stress-MPI results reported by 11 physicians.
Effect of ketosis induced by on delayed-onset muscle soreness, inflammation and redox status: a randomized, open-label, crossover pilot study.
J Sports Med Phys Fitness
January 2025
Department of Sports and Welfare Science, School of Physical Education, Sendai University, Shibata, Japan.
Background: Previous studies show that ketosis caused by the consumption of low-carbohydrate diets improves cognitive functions and that ketogenic diets can be used to treat epilepsy. In vivo and in vitro experiments have shown that ketosis regulates pain, inflammation, and oxidative stress. Thus, we investigated the effects of ketosis induced by a low-carbohydrate diet on muscle soreness, inflammation, and redox status in human subjects.
View Article and Find Full Text PDFBiomarkers.
Alzheimers Dement
December 2024
University of São Paulo Medical School, São Paulo, São Paulo, Brazil.
Background: Down syndrome (DS) is associated with mitochondrial dysfunction leading to higher levels of oxidative stress and cell degeneration. This fact, together with the overexpression of AD-related genes in trisomy 21, increases the risk of developing Alzheimer's disease (AD). Thus, it is important to look for interventions that could prevent mitochondrial damage before symptoms occur.
View Article and Find Full Text PDFBackground: Reducing risk of dementia requires a person to have accessible information about health and risk factors, person-centered health goals, and self-efficacy. Here, we test the feasibility of a new risk reduction program called Brain Wellness Information, Support, and Empowerment (Brain-WISE). Its unique features are that it (1) is aligned with a theoretical model of behavior change, (2) is relatively brief (six 90-min sessions), (3) is conducted with groups of people who have pre-existing community; (4) includes individual and group activities and person-centered health goals; and (5) is conducted with speech-language therapists.
View Article and Find Full Text PDFBackground: The Finnish Geriatric Intervention Study to Prevent Cognitive Impairment and Disability (FINGER) multimodal lifestyle intervention yielded cognitive and other health benefits in older adults at risk of cognitive decline. The two-year multinational randomized controlled LETHE trial evaluates the feasibility of a digitally supported, adapted FINGER intervention among at-risk older adults. Technology is used to complement in-person activities, for the intervention delivery, personalize recommendations, and collect digital biomarkers.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!