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http://dx.doi.org/10.1016/j.jaad.2019.03.068 | DOI Listing |
J Clin Invest
January 2025
Division of Rheumatology, Center of Excellence for Intestinal and Immunology Research, University of Alberta, Edmonton, Alberta, Canada.
Superantigen-induced (Sag-induced) autoimmunity has been proposed as a mechanism for many human disorders, without a clear understanding of the potential triggers. In this issue of the JCI, McCarthy and colleagues used the SKG mouse model of rheumatoid arthritis to characterize the role of Sag activity in inflammatory arthritis by profiling arthritogenic naive CD4+ T cells. Within the diseased joints, they found a marked enrichment of T cell receptor-variable β (TCR-Vβ) subsets that were reactive to the endogenously encoded mouse mammary tumor virus (MMTV) Sag.
View Article and Find Full Text PDFEur Radiol
January 2025
University of Toronto, Temerty Faculty of Medicine, Joint Department of Medical Imaging, Toronto, ON, Canada.
Eur Respir J
January 2025
Assistance Publique Hôpitaux Paris (AP-HP), Hôpital Bichat, Département de Médecine Interne, Paris, France
Europace
December 2024
Translational Cardiology, Department of Cardiology and Department of Physiology, Inselspital University Hospital Bern, University of Bern, Bern 3012, Switzerland.
J Endocr Soc
November 2024
2nd Department of Internal Medicine Research Unit and Diabetes Centre Attikon Hospital Medical School, National and Kapodistrian University of Athens, 12462 Athens, Greece.
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