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http://dx.doi.org/10.1177/0091415019836100 | DOI Listing |
Appl Neuropsychol Adult
January 2025
Neuropsychology and Cognitive Health Program, Baycrest Health Sciences, Toronto, Canada.
Objective: The Boston Naming Test (BNT) is commonly used to assess word-finding in older adults but performance may be impacted by cultural and linguistic factors. This study aimed to assess cultural bias in BNT performance among older adults, explore sources of this bias and provide clinical guidelines for its use in multicultural settings.
Methods: We conducted a retrospective chart review of 525 older adults referred for neuropsychological assessment at a large geriatric hospital in a multicultural Canadian city.
Front Endocrinol (Lausanne)
January 2025
Department of Clinical Medicine and Surgery, University of Naples Federico II, Naples, Naples, Italy.
Familial hypercholesterolemia (FH) is a genetic disease, usually with onset during childhood, characterized by elevated blood LDL cholesterol levels and potentially associated with severe cardiovascular complications. Concerning mutated genes in FH, such as , a small subset of FH patients presents a homozygous genotype, resulting in homozygous FH (HoFH) disease with a generally aggressive phenotype. Besides statins, ezetimibe and PCSK9 inhibitors, lomitapide (an anti-ApoB therapy) was also approved in 2012-2013 as an adjunctive treatment for HoFH.
View Article and Find Full Text PDFAge Ageing
January 2025
Medicine Clinical Board, University Hospital of Wales Cardiff, Cardiff, UK.
In response to increased focus on the issue of Assisted Dying (AD) in the UK due to the presentation of The Terminally Ill Adults (End of Life) Bill 2024-25 [1] and bills before parliaments in the Isle of Man, Guernsey and Scotland, the British Geriatric Society (BGS) recently developed a position statement opposing legalisation of AD in the UK [2]. We set out our key reasoning behind this position, namely the current adverse health and social care context and significant concern about whether effective safeguards can be created to protect older people with complex needs from undue harms. The BGS asks for improved, personalised, multidisciplinary care for older people at the end of their lives, including high-quality palliative and end-of-life care.
View Article and Find Full Text PDFPsychother Res
January 2025
Department of Psychology and Behavioral Sciences, Zhejiang University, Hangzhou, Zhejiang, People's Republic of China.
This study applied a mixed-methods approach to investigate rater effects that might affect case report evaluation in China. In the quantitative phase, we randomly assigned 210 mental health professionals to the experienced or novice ratee condition to rate the same structured case report on assessment and formulation, intervention strategy, relationship, and self-reflection. The qualitative phase was subsequently conducted to help make sense of the results.
View Article and Find Full Text PDFNutrients
December 2024
Universidad Autónoma de Nuevo León, Facultad de Salud Pública y Nutrición, Centro de Investigación en Nutrición y Salud Pública, Monterrey 64460, México.
Recent insights into the influence of nutrition on immune system components have driven the development of dietary strategies targeting the prevention and management of major metabolic-inflammatory diseases. This review summarizes the bidirectional relationship between nutrition and immunocompetence, beginning with an overview of immune system components and their functions. It examines the effects of nutritional status, dietary patterns, and food bioactives on systemic inflammation, immune cell populations, and lymphoid tissues, as well as their associations with infectious and chronic disease pathogenesis.
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