Value of DSC in Characterization and Optimization of Protein Stability.

Methods Mol Biol

MicroCal, Malvern Panalytical, Uppsala, Sweden.

Published: August 2019

Differential scanning calorimetry (DSC) is a well-established technique for biomolecular stability studies. The technique is based on forced thermal denaturation of biomolecules in solution. Here we describe the use of DSC for characterization and optimization of stability of two proteins, a protein kinase and a mAb protein.

Download full-text PDF

Source
http://dx.doi.org/10.1007/978-1-4939-9179-2_3DOI Listing

Publication Analysis

Top Keywords

dsc characterization
8
characterization optimization
8
optimization protein
4
protein stability
4
stability differential
4
differential scanning
4
scanning calorimetry
4
calorimetry dsc
4
dsc well-established
4
well-established technique
4

Similar Publications

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!