Postpartum depression (PPD) is a debilitating mental illness affecting approximately 13% of mothers after birth. Both genetic and psychosocial factors contribute to PPD risk, but very little is known about how these factors interact. We tested whether the rs53576 polymorphism in the oxytocin receptor (OXTR) gene accounts for variation in the impact of low social support as a risk factor for depression among mothers during the perinatal period. New mothers (N = 220) provided saliva or blood DNA samples and completed surveys assessing PPD symptoms and perceived social support. In a significant interaction, social support from the baby's father predicted PPD symptoms to a greater extent among mothers with the GG compared to AG and AA genotypes. These results add to converging evidence that variation in OXTR rs53576 moderates the impact of the social environment on PPD.
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http://dx.doi.org/10.1016/j.biopsycho.2019.03.015 | DOI Listing |
Med Decis Making
December 2024
Department of Social & Behavioral Sciences, College of Public Health, Temple University, Philadelphia, PA, USA.
Background: In the United States, human papillomavirus (HPV) vaccination among 27- to 45-y-olds (mid-adults) is recommended based on shared clinical decision making with a health care provider. We developed a patient decision aid tool to support the implementation of this mid-adult HPV vaccination guideline. The purpose of this study was to evaluate the effect of a patient decision aid tool for HPV vaccination, HPV DECIDE, compared with an information fact sheet among mid-adults who have not received the HPV vaccine.
View Article and Find Full Text PDFTrauma Violence Abuse
December 2024
College of Public Health, Department of Social Work, George Mason University, VA, USA.
Researchers are increasingly conducting research using primary source data involving observation of, and exposure to, violent extremist individuals, their acts, their online content, and the ideologies that they act in support of. Of concern is that this increased use of primary source material has not occurred alongside a serious investigation of the traumatic outcomes that may result from constant exposure to such materials within the process of conducting academic research. As such, the goal of this review is to conduct a rapid evidence assessment to identify (a) What theories currently exist that conceptualize trauma stemming from vicarious observation of extremist atrocities? (b) In what similar domains (if any) have researchers conceptualized the trauma that stems from vicarious observation of extremist atrocities? (c) What is the current evidence base for these theories? And (d) What are the immediate research needs to extend this research and support the research workforce? Articles were identified using search strings related to types of trauma, and relevant domains of work (e.
View Article and Find Full Text PDFMilbank Q
December 2024
Truman School of Government and Public Affairs, University of Missouri.
Unlabelled: Policy Points Policymakers should consider both material (e.g., cost) and attitudinal (e.
View Article and Find Full Text PDFTher Adv Musculoskelet Dis
December 2024
Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, Botnar Research Centre, Windmill Road, Oxford OX3 7HE, UK.
Background: Psoriatic arthritis (PsA) is a chronic inflammatory condition that can affect individuals of all ages. Patients may experience a range of physical and psychological issues.
Objective: To examine the impact of PsA on an individual's quality of life (QoL) and physical function.
Dialogues Health
December 2024
Bruyère Health Research Institute, Ottawa, Ontario, Canada.
Objective: The COVID-19 pandemic highlighted and exacerbated health inequities worldwide. While several studies have examined the impact of individual social factors on COVID infection, our objective was to examine how interactions of social factors were associated with the risk of testing positive for SARS-CoV-2 during the first two years of the pandemic.
Study Design And Setting: We conducted an observational cohort study using linked health administrative data for Ontarians tested for SARS-CoV-2 between January 1st, 2020, and December 31st, 2021.
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