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Therapeutic potential of ketone bodies on exercise intolerance in heart failure: looking beyond the heart.
Cardiovasc Res
January 2025
Cardiovascular Research Centre, University of Alberta, Edmonton, Alberta, Canada.
Recent evidence suggests that ketone bodies have therapeutic potential in many cardiovascular diseases including heart failure (HF). Accordingly, this has led to multiple clinical trials that use ketone esters to treat HF patients, which we term ketone therapy. Ketone esters, specifically ketone monoesters, are synthetic compounds which, when consumed, are de-esterified into two β-hydroxybutyrate (βOHB) molecules and increase the circulating βOHB concentration.
View Article and Find Full Text PDFEffects of a home-based multicomponent exercise programme on frailty in postcardiac surgery patients: A randomized controlled trial.
Eur J Cardiovasc Nurs
January 2025
Professor, College of Nursing, National Yang Ming Chiao Tung University, Taipei, Taiwan.
Aims: A randomized controlled trial was conducted to examine the effects of a home-based multicomponent exercise programme on frailty in patients who underwent cardiac surgery.
Methods And Results: A convenience sample of 92 patients who underwent cardiac surgery at two medical centres in Taiwan were recruited and randomly allocated to the intervention (n = 46) and control (n = 46) groups. The intervention group underwent a 12-week home-based multicomponent exercise programme, including individual nursing consultation, home-based exercise intervention, nutritional assessment and guidance, and continuous support.
Validation of an Aerobic Fitness Questionnaire to estimate VO peak in a cohort of adult cardiac patients - Is it enough?
Rev Port Cardiol
January 2025
Cardiology Department, Santa Cruz Hospital, Lisbon, Portugal; Cardiac Rehabilitation Unit, Santa Cruz Hospital, Lisbon, Portugal.
Introduction And Objectives: Cardiopulmonary exercise testing (CPET) is the gold standard for quantifying aerobic functional capacity, yet it is costly and not widely available. The CLINIMEX Aerobic Fitness Questionnaire (C-AFQ) may be a practical alternative as it estimates oxygen consumption at peak exercise (VO peak) based on patients' responses to a list of activities with known energy requirements. However, its applicability in cardiac patients is unclear and has not yet been studied.
View Article and Find Full Text PDFEffectiveness of 'Internet Plus' remote management in improving cardiac rehabilitation outcomes in acute myocardial infarction patients.
Am J Transl Res
December 2024
Nursing Department, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine Hangzhou 310000, Zhejiang, China.
Objectives: This study evaluated the effectiveness of "Internet Plus" remote management in enhancing cardiac rehabilitation outcomes for patients with acute myocardial infarction (AMI) following percutaneous coronary intervention (PCI).
Methods: A total of 101 AMI patients post-PCI from Sir Run Run Shaw Hospital were included between December 2021 and November 2022. Patients were retrospectively categorized into two groups based on the type of care they received: the control group receiving standard post-PCI rehabilitation, and the observation group receiving remote management via "Internet Plus" for six months.
Canadian Stroke Best Practice Recommendations: Vascular cognitive impairment, 7th edition practice guidelines update, 2024.
Alzheimers Dement
January 2025
Department of Clinical Neurosciences, University of Calgary, Calgary, Canada.
The Canadian Stroke Best Practice Recommendations (CSPR) 7th edition includes this new module on the diagnosis and management of vascular cognitive impairment (VCI) with or without neurodegenerative disease. An expert writing group and people with VCI lived experience (PWLE) reviewed current evidence. Existing recommendations were reviewed and revised, and new recommendations added.
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