Prevalence of cervical cancer and pre-cancerous lesions among unscreened Women in Kumasi, Ghana.

Medicine (Baltimore)

Department of Pathology, School of Biomedical and Allied Health Sciences, College of Health Sciences, University of Ghana, Ghana.

Published: March 2019

AI Article Synopsis

  • Ghana lacks a universal cervical cancer screening program, leading to limited data on the prevalence of cervical epithelial cell lesions among women.
  • A study conducted in Kumasi from 2011 to 2014 found a moderately high prevalence of cervical cancer and precancerous lesions in women who had not been screened before.
  • Out of 592 Pap smears assessed, 3.7% showed abnormalities, highlighting the need for routine cervical cancer screening to allow for early detection and management in Ghana.

Article Abstract

Ghana does not have a universal population-based cervical cancer screening program and there is very limited information about the distribution of cervical epithelial cell lesions. This study provides evidence that a moderately high prevalence of cervical cancer and precancerous lesions exists among unscreened women in Kumasi.The prevalence of cervical epithelial cell abnormalities among a cross-section of women attending cervical cancer screening for the first time in a suburb of Ghana from 2011 to 2014 was studied. Cervical smears were prepared and examined independently by 2 cytotechnologists and confirmed by a pathologist. Cervical lesions were classified according to the Bethesda System for cervical cytology 2001.Out of the 592 women for whom a Pap smear was available for evaluation, 555 (93.8%) were negative for intraepithelial lesion or malignancy. Eight women (1.4%) showed atypical squamous cells of undetermined significance (ASCUS), 9 (1.4%) low-grade squamous intraepithelial lesions, and 2 (0.3%) high-grade squamous intraepithelial lesions. A total of 15 (2.5%) smears were unsatisfactory for cervical cytology. Additionally, 3 women (0.5%) had squamous cell carcinoma, giving an overall rate of 3.7% for epithelial cell abnormalities.Cervical cancer and precursor epithelial cell abnormalities are common among women in Kumasi for a disease that can be prevented by early detection through routine screening and management. This study provides adequate background data to recommend the implementation of cervical cancer screening in all eligible women in Ghana.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6456016PMC
http://dx.doi.org/10.1097/MD.0000000000014600DOI Listing

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