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Gene cloning to clinical trials-the trials and tribulations of a life with collagen. | LitMetric

Gene cloning to clinical trials-the trials and tribulations of a life with collagen.

Int J Exp Pathol

Wellcome Centre for Cell-Matrix Research, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester, UK.

Published: February 2019

This review, based on the BSMB Fell-Muir Lecture I presented in July 2018 at the Matrix Biology Europe Conference in Manchester, gives a personal perspective of my own laboratory's contributions to research into type X collagen, metaphyseal chondrodysplasia type Schmid and potential treatments for this disorder that are currently entering clinical trial. I have tried to set the advances made in the context of the scientific technologies available at the time and how these have changed over the more than three decades of this research.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6463393PMC
http://dx.doi.org/10.1111/iep.12311DOI Listing

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