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A framework towards implementation of sequencing for antimicrobial-resistant and other health-care-associated pathogens.
Lancet Infect Dis
January 2025
Division of Healthcare Quality Promotion, Centers for Disease Control and Prevention, Atlanta, GA, USA.
Antimicrobial resistance continues to be a growing threat globally, specifically in health-care settings in which antimicrobial-resistant pathogens cause a substantial proportion of health-care-associated infections (HAIs). Next-generation sequencing (NGS) and the analysis of the data produced therein (ie, bioinformatics) represent an opportunity to enhance our capacity to address these threats. The 3rd Geneva Infection Prevention and Control Think Tank brought together experts to identify gaps, propose solutions, and set priorities for the use of NGS for HAIs and antimicrobial-resistant pathogens.
View Article and Find Full Text PDFLifecycle of an introduced (Bucephalidae) trematode in the Tone River system, Japan.
J Helminthol
January 2025
Toho University, Faculty of Science, 2-2-1 Miyama, Funabashi, Chiba274-8510, Japan.
During 2021 through 2023, the golden mussel and freshwater fishes were sampled from 28 sites in the Tone River system, Japan, and adult trematodes of were found in the fishes. Molecular and morphological analyses based on 28S rDNA and the ITS1-5.8S-ITS2 region revealed the trematode as '', previously reported in Mainland China and likely introduced to Japan.
View Article and Find Full Text PDFThe time for regionalised vaccine manufacturing has arrived.
Lancet
January 2025
Executive Committee, Regionalized Vaccine Manufacturing Collaborative (RVMC), Oslo, Norway.
Study protocol for a multi-center stepped-wedge cluster randomized trial to explore the usability and outcomes among young people living with HIV in Kiambu and Kirinyaga counties of Kenya, using an online health portal.
PLOS Digit Health
January 2025
Johnson & Johnson Global Public Health, Janssen Pharmaceutica NV, Beerse, Belgium.
While the incidence of Human Immunodeficiency Virus (HIV) infection is decreasing in most age groups worldwide, it is rising among adolescents and young adults, who also face a higher rate of HIV-related deaths. This tech-savvy demographic may benefit from an online patient portal designed to enhance patient activation-empowering them to manage their health independently. However, the effectiveness of such digital health interventions on young HIV patients in Kenya remains uncertain.
View Article and Find Full Text PDFLeveraging digital health systems maturity assessments to guide strategic priorities.
J Public Health Afr
December 2024
Department of Global Health, University of Washington, Seattle, United States of America.
Background: Many low- and middle-income countries (LMICs) face the daunting task of digitising, maturing and deciding where to invest in digital health systems.
Aim: Describing the facilitators and barriers to conducting digital health maturity assessments and how health leaders can prioritise the assessments.
Setting: eHealth leaders from 10 African countries, working or supporting Ministries of Health's digital health and participating in the eHealth Leaders' Forum from July 2023 to September 2023.
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