Strain SCT is an iodate-reducing bacterium isolated from marine sediment in Kanagawa Prefecture, Japan. In this study, we determined the draft genome sequence of strain SCT and compared it to complete genome sequences of other closely related bacteria, including A phylogeny inferred from concatenation of core genes revealed that strain SCT was closely related to marine isolates of Genes present in the SCT genome but absent from the other analyzed genomes comprised clusters corresponding to putative prophage regions and possible operons. They included genes, which encode type IV pili for natural transformation; the operon, which encodes resistance systems for mercury; and the operon, which encodes a Pi-specific transport system for phosphate uptake. We found that strain SCT had more prophage-like genes than the other strains and that the majority (70%) of them were SCT strain-specific. These genes, encoded on distinct prophage regions, may have been acquired after branching from a common ancestor following independent phage transfer events. Thus, the genome sequence of sp. strain SCT can provide detailed insights into its metabolic potential and the evolution of genetic elements associated with its unique phenotype.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6505155 | PMC |
| http://dx.doi.org/10.1534/g3.118.200978 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Conjugation Mediates Large-Scale Chromosomal Transfer in Streptomyces Driving Diversification of Antibiotic Biosynthetic Gene Clusters.
Mol Biol Evol
November 2024
Université de Lorraine, INRAe, DynAMic, Nancy, F-54000, France.
Streptomyces are ubiquitous soil-dwelling bacteria with large, linear genomes that are of special importance as a source of metabolites used in human and veterinary medicine, agronomy, and industry. Conjugative elements (actinomycetes integrative and conjugative elements, AICEs) are the main drivers of Streptomyces Horizontal Gene Transfer. AICE transfer has long been known to be accompanied by mobilization of chromosomal DNA.
View Article and Find Full Text PDFPreventing Allogeneic Stem Cell Transplant-Related Cardiovascular Dysfunction: ALLO-Active Trial.
Circulation
November 2024
Baker Heart and Diabetes Institute, Melbourne, Australia (H.T.D., N.J.S., T.I., C.J.B., D.W.D., N.O., B.M.L., E.J.H.).
Background: Allogeneic stem cell transplantation (allo-SCT) is an efficacious treatment for hematologic malignancies but can be complicated by cardiac dysfunction and exercise intolerance impacting quality of life and longevity. We conducted a randomized controlled trial testing whether a multicomponent activity intervention could attenuate reductions in cardiorespiratory fitness and exercise cardiac function (co-primary end points) in adults undergoing allo-SCT.
Methods: Sixty-two adults scheduled for allo-SCT were randomized to a 4-month activity program (n=30) or usual care (UC; n=32).
Tactile stimulation of young WAG/Rij rats prevents development of depression but not absence epilepsy.
Front Behav Neurosci
June 2024
Department of Physiology, Faculty of Medicine, Kocaeli University, İzmit, Türkiye.
Article Synopsis
- Scientists studied rats that have a type of epilepsy and found that touching the rats gently can help them feel better.
- They divided the rats into three groups: one group got touched, one was just handled, and one was left alone.
- After several weeks, the rats that were touched showed better moods and less seizure activity compared to the other groups.
The Scratch-Collapse Test: Are Electrodiagnostic Changes Measurable?
Ann Plast Surg
September 2024
Department of Orthopaedic Surgery, University of California, Los Angeles, Los Angeles, CA.
Introduction: Carpal tunnel syndrome is commonly managed by hand and upper extremity surgeons. Though electrodiagnostics are considered the gold standard diagnosis, the scratch collapse test (SCT) was introduced to address uncertainty, despite remains controversial. To address this, we sought to identify if the SCT can correlate with EDS studies if the SCT can identify actual changes in measures of nerves.
View Article and Find Full Text PDFSubchondral bone fatigue injury in the parasagittal condylar grooves of the third metacarpal bone in thoroughbred racehorses elevates site-specific strain concentration.
J Mech Behav Biomed Mater
July 2024
Department of Mechanical Engineering, University of Wisconsin-Madison, Madison, WI, 53706, USA; Department of Biomedical Engineering, University of Wisconsin-Madison, Madison, WI, 53706, USA; Department of Orthopedics and Rehabilitation, University of Wisconsin-Madison, Madison, WI, 53705, USA. Electronic address:
Article Synopsis
- Condylar stress fractures in the distal end of third metacarpal/metatarsal bones are a leading cause of injury and euthanasia in racehorses.
- This study aimed to investigate whether focal subchondral bone injuries influence strain in the condyles using advanced imaging techniques and mechanical testing.
- Results showed that bones with subchondral bone injury had significantly higher strain rates in the parasagittal groove, indicating a link between structural changes and increased risk of stress fractures.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!