Purpose: To evaluate impact of polar renal artery coverage on early renal function after chimney endovascular aneurysm repair (EVAR).
Materials And Methods: Consecutive patients who underwent chimney EVAR for treatment of asymptomatic juxtarenal abdominal aortic aneurysm were retrospectively included. Estimated glomerular filtration rate (eGFR) was recorded before the intervention and at 1-, 5-, 7-, and 30-day follow-up. Patients without a polar renal artery were compared with patients with an uncovered polar renal artery and patients with a polar renal artery covered by the endograft.
Results: Among 76 patients who underwent chimney EVAR, 15 (19.7%) had a polar renal artery. Four patients (5.3%) had an uncovered polar renal artery and 11 (14.5%) had a covered polar renal artery. The median polar renal artery diameter was 3.3 mm (interquartile range, 2.2-3.8 mm). Preoperative eGFR was similar between the 3 groups (65.5 mL/min/1.73 m, 61.1 mL/min/1.73 m, and 53 mL/min/1.73 m, P = .488). For the 3 groups, postoperative eGFR tended to decrease after the intervention compared with preoperative values, and this decrease reached statistical significance at 5 days and 30 days in patients without a polar renal artery. No significant difference was observed between the 3 groups at any time point. No correlation was observed between the diameter of the covered polar renal artery and eGFR changes postoperatively.
Conclusions: Polar renal artery coverage during chimney EVAR does not significantly impair early renal postoperative function, suggesting the safety of the procedure.
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http://dx.doi.org/10.1016/j.jvir.2018.11.031 | DOI Listing |
Cureus
December 2024
Department of Surgery, Center for Anatomical Science and Education, Saint Louis University School of Medicine, Saint Louis, USA.
Two unique presentations of renal anatomy were observed during routine cadaveric dissection. The first case presented with an ectopic malrotated left kidney supplied by supernumerary renal arteries. This kidney was drained by a circumaortic renal vein and an inferior polar vein.
View Article and Find Full Text PDFInt J Biol Macromol
December 2024
Key Laboratory of Tropical Translational Medicine of Ministry of Education, Hainan Provincial Key Laboratory of Research and Development on Tropical Herbs, Haikou Key Laboratory of Li Nationality Medicine, School of Pharmacy, Hainan Medical University, Haikou 571199, China. Electronic address:
The use of natural polysaccharides from traditional Chinese medicine as carrier materials has great potentiality in drug delivery. Nootkatone (NKT) demonstrated good pharmacological activity in treating kidney injury, but its solubility and bioavailability are not very good which may affect the effectiveness of its therapeutic effect. Alpinia oxyphylla fructus polysaccharide (AOP), as a plant polysaccharide, has multiple pharmacological activities and may help to provide synergy for NKT.
View Article and Find Full Text PDFAm J Physiol Cell Physiol
December 2024
Department of Urology, Xiangya Hospital, Central South University, Changsha 410000, Hunan Province, P.R. China.
The disease burden of renal cell carcinoma (RCC) has decreased in recent years with advances in treatment, but its pathogeny still remains elusive. We aim to study the role of HOXA3/USP15/SQSTM1 axis on autophagy and M2-type macrophage polarization in RCC. In this study, cell apoptosis and proliferation were assessed by flow cytometry and CCK-8.
View Article and Find Full Text PDFJ Inflamm Res
December 2024
Department of Traditional Chinese Medicine, The First Affiliated Hospital of Jinan University, Guangzhou, People's Republic of China.
Purpose: This study aimed to examine the impact of APS on acute kidney injury induced by rhabdomyolysis (RIAKI), exploring its association with macrophage M1 polarization and elucidating the underlying mechanisms.
Methods: C57BL/6J mice were randomly assigned to one of three groups: a normal control group, a RIAKI model group, and an APS treatment group. Techniques such as flow cytometry and immunofluorescence were employed to demonstrate that APS can inhibit the transition of renal macrophages to the M1 phenotype in RIAKI.
J Natl Cancer Cent
December 2024
Department of Urology, Fudan University Shanghai Cancer Center, Shanghai, China.
Background: Completely endophytic renal tumors (CERT) pose significant challenges due to their anatomical complexity and loss of visual clues about tumor location. A facile scoring model based on three-dimensional (3D) reconstructed images will assist in better assessing tumor location and vascular variations.
Methods: In this retrospective study, 80 patients diagnosed with CERT were included.
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