AI Article Synopsis
- - The research on M cells, which are specialized cells in the immune system, faces challenges due to the absence of a universal marker for reliable identification.
- - Many existing studies struggle to confirm whether their findings truly involve M cells or if other undetected factors are influencing their results.
- - This review aims to assess current M cell markers used in research and suggests a standardized approach for identifying M cells in future studies, potentially enhancing the quality of published work in this area.
Article Abstract
The study of M cells, a specialized epithelial cell type found in the follicle-associated epithelium, is hampered by the lack of a universal M cell marker. As such, many studies lack reliable and universally recognized methods to identify M cells in their proposed models. As a result of this it is difficult to ascertain whether the effects observed are due to the presence of M cells or an unaccounted variable. The outcome of this review is the thorough evaluation of the many M cell markers that have been used in the literature thus far and a proposed criterion for the identification of M cells for future publications. This will hopefully lead to an improvement in the quality of future publications in this field.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6545693 | PMC |
| http://dx.doi.org/10.1177/1535370219838674 | DOI Listing |
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