To demonstrate the affection of skull base by mucormycosis in an immunocompetent individual. Mucormycosis is an opportunistic infection principally seen in immunocompromised individuals, but recently being increasingly recognized in otherwise healthy individuals. Skull base involvement secondary to otogenic nidus, mimicking otitis media was rarely reported. A 34 year-old male, an otherwise healthy patient presented with facial nerve palsy followed by trismus, neck swelling and neck stiffness. Radical mastoidectomy with tympanoplasty and Facial nerve decompression along with Endoscopic guided debridement of sinuses and pterygopalatine fossa followed by medical treatment for 14 weeks. Facial nerve functioning, dry ear canal and relief from other symptoms. Surgical debridement and post op Anti fungal treatment improved the facial nerve function to House brackmann grade-II and also provided relief from trismus and stiffness and improved the overall general condition of the patient. Mucor is a saprophytic organism, which can cause extensive progression, regardless of the immune status. To the best of our knowledge, this is one of the very few rare cases that have been reported in the context of skull base mucormycosis in immunocompetent individuals. Surgical debridement followed by anti fungal therapy continues to remain the mainstay of treatment.
Download full-text PDF |
Source |
---|---|
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6401032 | PMC |
http://dx.doi.org/10.1007/s12070-018-1428-y | DOI Listing |
Neurosurg Rev
January 2025
Department of Cariology, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences (SIMATS), Chennai, India.
Diagn Cytopathol
January 2025
Department of Neurosurgery, Medical University of South Carolina, Charleston, South Carolina, USA.
Solitary plasmacytomas are localized single tumors of monoclonal plasma cells that occur in two variants: solitary plasmacytoma of bone and extraosseous plasmacytoma. Solitary plasmacytoma of bone accounts for only 1%-2% of plasma cell lesions, and extraosseous plasmacytoma is also approximately 1%. These are both very uncommon at the skull base.
View Article and Find Full Text PDFClin Otolaryngol
January 2025
School of Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan.
Introduction: The nasoseptal flap (NSF) has become a widely favoured choice for reconstructing skull base defects following the endoscopic endonasal approach (EEA). However, the exposed septal cartilage and bone at the donor site often require an extended duration for secondary healing. This study investigated whether the free middle turbinate (MT) mucosa grafting at the septal donor site could mitigate post-operative nasal morbidity.
View Article and Find Full Text PDFJ Neurol Surg Rep
January 2025
Intent Medical Group, Department of Neurosciences, Northwest Community Hospital, Part of Endeavor Health, Arlington Heights, Illinois, United States.
Nasopharyngeal stenosis is a challenging condition characterized by a narrowed nasopharynx, leading to nasal congestion, impaired breathing, and recurrent sinus issues. In this report, we present a unique surgical approach that combines the use of both the Da Vinci Xi robot and a 70-degree nasal endoscope in a patient with a type II stenosis of the nasopharynx. The benefits of improved visualization, maneuverability, and precision of this novel combined approach are highlighted.
View Article and Find Full Text PDFJCEM Case Rep
February 2025
Department of Endocrine Neoplasia and Hormonal Disorders, The University of Texas MD Anderson Cancer, Houston, TX 77030, USA.
A 65-year-old patient presented with recurrent, locally advanced poorly differentiated thyroid cancer despite 2 neck surgeries, and with newly diagnosed brain and skull base metastases. He was treated with palliative stereotactic radiosurgery to the brain and skull base lesions. Thereafter, as no targetable genetic alteration was identified and antiangiogenic multikinase inhibitors were deemed at high risk of hemorrhagic complications, off-label systemic therapies were considered.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!