Neocord formation after Type III cordectomy is insufficient for complete glottic closure due to scarring and soft tissue deficit. This study evaluates the role of autologous fat injection (AFI) in phonosurgical management of patients who have previously undergone Type III cordectomy for early glottic cancer. Data was collected from hospital records of patients who underwent AFI after previously undergoing Type III cordectomy. A minimum duration of 6 months post-cordectomy was maintained before fat injection. Trans-oral injection was performed at a single site. Pre-operative voice evaluation was done using VHI, GRBAS scale and MDVP software. Post-operative evaluation was done at 6 weeks. 21 out of 62 post-Type III cordectomy patients chose to undergo fat augmentation and were included in the study. A comparison of pre-operative and 6 months post-operative AFI voice analysis showed a significant improvement in VHI, all parameters of GRBAS scale, and improvement in Jitter, Shimmer, SPI and NHR. There was a decrease in fundamental frequency but this was not statistically significant. AFI is an effective procedure for surgical voice rehabilitation of patients who have undergone Type III cordectomy for early laryngeal cancer.
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http://dx.doi.org/10.1007/s12070-018-1543-9 | DOI Listing |
Diagnostics (Basel)
January 2025
Department of Otorhinolaryngology and Head and Neck Surgery, University Hospital Center Sestre Milosrdnice, 10000 Zagreb, Croatia.
: The study aims to analyse the factors associated with positive margins and endoscopic understaging in laryngeal carcinoma. It also aims to assess the diagnostic accuracy of Narrow Band Imaging (NBI) in comparison to White Light Endoscopy (WLE) and other diagnostic methods. : In this retrospective comparative cohort analysis, 206 patients who underwent endoscopic laser surgery for T1 and T2a glottic squamous cell carcinoma between 1 January 2016 and 30 April 2023 were included.
View Article and Find Full Text PDFJ Clin Med
November 2024
Otorhinolaryngology-Head and Neck Surgery, Department of Diagnostic Clinical and Public Health, University of Modena and Reggio Emilia, 41125 Modena, Italy.
The recommended treatment for early glottic cancer is trans-oral laser microsurgery, with excellent oncological and functional outcomes. The aim of this study is to evaluate oncological and functional outcomes in patients who underwent monolateral type III laser cordectomy for early glottic cancer. A total of 104 patients were enrolled.
View Article and Find Full Text PDFOtolaryngol Head Neck Surg
February 2025
Research Committee, Young Otolaryngologists of the International Federation of Otorhinolaryngological Societies (IFOS), Paris, France.
Objectives: To compare the presurgical to postsurgical voice quality (VQ) outcomes of types I, II, III, and VI transoral laser cordectomies (TLC).
Study Design: Prospective uncontrolled study.
Setting: Multicenter study.
Cancer Radiother
August 2024
ENT and Head and Neck Surgery Department, hôpital Huriez, université de Lille, Lille, France; « Cancer Heterogeneity, Plasticity and Resistance to Therapies » (CANTHER), centre Oscar-Lambret, UMR9020 CNRS, U1277 Inserm, CHU de Lille, université de Lille, 59037 Lille cedex, France. Electronic address:
Purpose: Many series have compared voice quality after radiotherapy or surgery for cT1 glottic carcinoma. Different meta-analyses identify better results for radiotherapy while others do not identify any difference, some finally find a superiority of surgery. The purpose of this study was to compare the voice quality in the long term of patients who underwent transoral surgery versus exclusive irradiation for the treatment of cT1 glottic carcinoma.
View Article and Find Full Text PDFActa Clin Croat
October 2022
Department of Ear, Nose, Throat and Head and Neck Surgery, Zagreb University Hospital Center, Zagreb, Croatia.
Laryngeal carcinoma is one of the most common tumors of the head and neck, just after skin cancer. Alongside open surgery, transoral endoscopic laser surgery (TOLS) has become widespread as a treatment method. Our aim was to assess the efficacy of transoral laser cordectomy in a group of patients with early glottic carcinoma.
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