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Article Synopsis
- The urachus is a leftover structure from fetal development that connects the bladder to the belly button, and cancers arising from it, known as primary urachal carcinoma, are rare but aggressive.
- A case study presents a 48-year-old woman with abdominal pain and a mass, which was diagnosed as squamous cell carcinoma after imaging and biopsy.
- Treatment typically involves surgery to remove the tumor and surrounding tissue to reduce the chance of spreading, but guidelines are sparse due to the rarity of this type of cancer, with current protocols based on limited data.
Targeted Genetic Sequencing Analysis of 223 Cases of Pseudomyxoma Peritonei Treated by Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy Shows Survival Related to GNAS and KRAS Status.
Cancer Med
October 2024
Human Development and Health, Faculty of Medicine, University of Southampton, Southampton, UK.
Background And Aim: Pseudomyxoma peritonei (PMP) is an unusual condition with unique behaviour caused by a mucinous neoplasm, usually arising from the appendix. The aim of this study was to evaluate the prevalence of genomic alterations in clinical specimens of PMP using a targeted assay and correlate the findings with clinical, pathological and outcome data. Sequencing data from 223 patients were analysed.
View Article and Find Full Text PDFUrachal adenocarcinoma with cervical invasion misdiagnosed as primary cervical adenocarcinoma: a case report and literature review.
Front Oncol
September 2024
Department of Gynecology and Obstetrics, West China Second University Hospital, Sichuan University, Chengdu, Sichuan, China.
Article Synopsis
- * This case study details a female patient misdiagnosed with cervical adenocarcinoma, who eventually underwent multiple surgeries and chemotherapy after being correctly identified with urachal adenocarcinoma that spread to the bladder and vagina.
- * The findings emphasize the need for thorough histopathological evaluation for accurate diagnosis and suggest that anterior pelvic exenteration may be an effective treatment for local recurrences of UrC, although more research is needed.
Bladder transitional cell carcinoma anatomic primary site as a predictor of survival and mortality: a population-based retrospective cohort study.
Ann Med Surg (Lond)
October 2024
School of Medicine and Medical Sciences, Holy Spirit University of Kaslik, Jounieh, Lebanon.
Background: Bladder cancer is a heterogeneous disease with varying prognostic outcomes based on the primary tumor site within the bladder. This study aims to evaluate the impact of tumor location on overall survival and cancer-specific survival in bladder cancer patients.
Methods: The authors conducted a retrospective cohort study using data from the Surveillance, Epidemiology, and End Results database.
Unmasking a Rare Cause of Acute Abdomen in Adults: A Case Report of an Infected Urachal Cyst.
Cureus
August 2024
Emergency Department, Cliniques Universitaires Saint Luc, Brussels, BEL.
Article Synopsis
- The urachus is a fetal structure that usually becomes a fibrous cord after birth, but sometimes it doesn't fully close, leading to the formation of urachal cysts and other abnormalities.
- These cysts are often asymptomatic and can go undetected, with infections being a major complication that may be misdiagnosed due to their subtle signs and varied symptoms.
- The case study involves a 48-year-old man who experienced acute abdominal pain, was diagnosed with an infected urachal cyst through imaging, and successfully treated with antibiotics and surgery.
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