AI Article Synopsis
- Nine new meroterpenoids (Zizhines G-O) and seven known analogs were extracted from the dried fruiting bodies of Ganoderma sinensis.
- Their structures were determined through spectroscopic analysis and comparison of CD curves.
- Selected new meroterpenoids showed significant inhibitory activity against AchE at a concentration of 50 μM.
Article Abstract
Zizhines G-O (1-9), nine new meroterpenoids, and seven known analogs (10-16) were isolated from the dried fruiting bodies of Ganoderma sinensis. Their structures were identified by using spectroscopic data and CD curve comparison. The inhibitory activities of the selected new meroterpenoids toward AchE were assessed in vitro. Compounds 1-6 and 10-14 were found to exhibit AchE inhibitory activities at the concentration of 50 μM.
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| http://dx.doi.org/10.1016/j.fitote.2019.03.016 | DOI Listing |
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