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ERS/ATS Global Lung Function Initiative normal values and classifying severity based on z-scores instead of per cent predicted.
Breathe (Sheff)
October 2024
Pulmonary Function Testing, Department of Pulmonary Medicine, Medisch Spectrum Twente, Enschede, The Netherlands.
Among the most discussed issues in the field of pulmonary function testing are reference equations and standardised methods of interpreting pulmonary function test (PFT) results. The Global Lung Function Initiative (GLI) task force gathered information from multiple countries with diverse ethnicities to create a multi-ethnic reference formula suitable for a broad age range. Their first output was the GLI-2012 spirometry reference equations.
View Article and Find Full Text PDFCompatibility of the global lung function 2012 spirometry reference values in children, adolescents and young adults: a systematic review.
Expert Rev Respir Med
November 2024
Department of Physiotherapy, State University of Santa Catarina (UDESC), Florianópolis, Brazil.
Introduction: The Global Lung Function Initiative (GLI 2012) has published multiethnic spirometry reference values. To identify studies that evaluated the compatibility (applicability, validity, representativeness, agreement and/or adequacy) of the reference equations proposed by the GLI 2012 for spirometry tests in different populations.
Methods: Systematic searches were carried out on the PubMed, LILACS (Latin American and Caribbean Health Sciences Literature), Scopus, Web of Science and Google Scholar databases.
Background And Aims: Although Spinal Anesthesia (SA) remains the technique of choice for many surgeries below the umbilicus, it is associated with multiple intraoperative complications. Sympathetic blockade and Bezold-Jarisch reflex do not fully explain SA-related cardiopulmonary complications. Reduction in FEV has been reported as a predictor of sudden cardiac death.
View Article and Find Full Text PDFDifferences in percentage predicted spirometric values obtained with thirteen reference equations applied to healthy children.
J Asthma
October 2024
Department of Paediatric Respiratory Medicine, Hospital El Pino, University of Santiago de Chile (USACH), Santiago, Chile.
Background: There is limited information on the discrepancy between the spirometric values calculated with diverse spirometric prediction equations in normal children.
Objective: To determine the differences in percentage predicted (PP) values calculated through thirteen prediction equations (PEs) in healthy Chilean children.
Methods: We compared the PP values for FVC, FEV1, FEF25-75% and FEV1/FVC obtained by applying thirteen PEs, using GLI-2012 as a gold standard reference equation and including race neutral GLI-2022 in the analysis; PP values are from a group of 208 healthy Chilean children aged 7 to 17 years.
Role of fractional exhaled nitric oxide in patients with sickle cell disease.
An Pediatr (Engl Ed)
October 2024
Sección de Neumología Infantil, Servicio de Pediatría, Hospital General Universitario Gregorio Marañón, Madrid, Spain.
Article Synopsis
- Patients with sickle cell disease show varying pulmonary function test results, but the significance of the fractional exhaled nitric oxide (FeNO) test in these patients is not well understood.
- A study conducted on 43 patients aged 6-18 years indicated no significant links between elevated FeNO levels and asthma diagnosis, spirometry patterns, or symptoms typically associated with asthma.
- However, a notable association was found between elevated FeNO levels and peripheral eosinophilia, suggesting that airway inflammation mechanisms may differ for patients with sickle cell disease.
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