Novel polysiloxane-based rhodamine B fluorescent probe for selectively detection of Al and its application in living-cell and zebrafish imaging.

Polysiloxanes have excellent stability and biological relevance and are suitable for biological research. However, there were few polysiloxane-based fluorescent probes for bioimaging. This report successfully designed a new polysiloxane-based polymer fluorescent probe (RB-1) for the first time as a "turn-on" fluorescent probe response to Al ion with highly sensitive and selectivity. Importantly, this probe could also apply both in cell and zebrafish imaging, indicating the huge application development prospects of polysiloxane-based fluorescent probes in future.