Fluorodeoxyglucose-positron emission tomography/computed tomography features of suspected solitary pulmonary lesions in breast cancer patients following previous curative treatment.

Thorac Cancer

Department of Molecular Imaging and Nuclear Medicine, National Clinical Research Center for Cancer, Tianjin Key Laboratory of Cancer Prevention and Therapy, Tianjin's Clinical Research Center for Cancer, Tianjin Medical University Cancer Institute and Hospital, Tianjin, China.

Published: May 2019

Background: Differentiating pulmonary metastasis from primary lung cancer can be challenging in patients with breast malignancy. This study aimed to characterize the imaging features of fluorodeoxyglucose-positron emission tomography/computed tomography ( F-FDG-PET/CT) for distinguishing between these diseases.

Methods: We enrolled 52 patients who received curative treatment for breast cancer but later presented with suspected solitary pulmonary lesions (SPLs) and subsequently underwent F-FDG-PET/CT to investigate.

Results: Subsolid lesions, ill-defined borders, lung lesions with negative maximum standardized uptake value, and lesions without F-FDG-PET/CT-diagnosed hilar and/or mediastinal lymph nodes and pleural metastases were more likely to be associated with primary lung cancer.

Conclusions: CT border, FDG uptake, hilar and/or mediastinal lymph node metastasis, and pleural metastasis are potential markers for diagnosis.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6500976PMC
http://dx.doi.org/10.1111/1759-7714.13049DOI Listing

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