Introduction: The ever expanding advances in various domains of cardiac and endovascular interventions has drawn tremendous attention toward the importance of the anatomical variability and morphometric parameters of the aortic arch (AA) and its branches.
Methods: The current study delineates the morphometry and anatomical variations of the AA branches by evaluating coronal, axial and sagittal CT multiplanar reformatted three-dimensional angiograms. Correlations between morphometric data as well as the distribution of morphometric data in relation to the anatomical variations were also illustrated.
Results: 35% of the examined AA showed abnormal branching patterns, the most common of which was the "bovine arch" (24%), followed by common ostium variant (6%) and aberrant left vertebral artery arising directly from AA (5%). The outer diameter of AA at its origin and its end was 33.83 and 22.06 mm, respectively. The distance between the origin of AA and the origin of brachiocephalic trunk (BCT), left common carotid artery (LCCA) and left subclavian artery (LSA) was 19.59, 23.01 and 26.01 mm, respectively. The outer diameter of BCT, LCCA and LSA was 15.7, 11.42 and 14.02 mm, respectively. The angles between the AA and the BCT, LCCA and LSA were 59.01°, 68.59° and 59.92°, respectively. The mean distance between the BCT and LCCA was 19.59 mm and the distance between the LCCA and the LSA was 23.01 mm. Significant positive and negative correlations between morphometric data as well as the distribution of morphometric parameters in relation to the anatomical variations have been identified.
Conclusion: The illustrated anatomical variations and morphometric data provide cardinal information especially for patients undergoing aortic endovascular intervention, principally for choosing the size, shape and type of the angiographic catheters and devices to be delivered.
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http://dx.doi.org/10.1007/s00276-019-02215-w | DOI Listing |
Nat Commun
January 2025
Digital Biomarkers for Oncology Group, German Cancer Research Center (DKFZ), Heidelberg, Germany.
Accurate melanoma diagnosis is crucial for patient outcomes and reliability of AI diagnostic tools. We assess interrater variability among eight expert pathologists reviewing histopathological images and clinical metadata of 792 melanoma-suspicious lesions prospectively collected at eight German hospitals. Moreover, we provide access to the largest panel-validated dataset featuring dermoscopic and histopathological images with metadata.
View Article and Find Full Text PDFJ Neurosci
January 2025
Brainnetome Center, Institute of Automation, Chinese Academy of Sciences, Beijing 100190, China
Genetic information is involved in the gradual emergence of cortical areas since the neural tube begins to form, shaping the heterogeneous functions of neural circuits in the human brain. Informed by invasive tract-tracing measurements, the cortex exhibits marked interareal variation in connectivity profiles, revealing the heterogeneity across cortical areas. However, it remains unclear about the organizing principles possibly shared by genetics and cortical wiring to manifest the spatial heterogeneity across cortex.
View Article and Find Full Text PDFOper Neurosurg (Hagerstown)
February 2025
Rhoton Neurosurgery and Otolaryngology Surgical Anatomy Program, Mayo Clinic, Rochester , Minnesota , USA.
Background And Objectives: The coexistence of complete carotico-clinoid bridge (CCB), an ossification between the anterior (ACP) and the middle clinoid (MCP), and an interclinoidal osseous bridge (ICB), between the ACP and the posterior clinoid (PCP), represents an uncommonly reported anatomic variant. If not adequately recognized, osseous bridges may complicate open or endoscopic surgery, along with the pneumatization of the ACP, especially when performing anterior or middle clinoidectomies.
Methods: According to Preferred Reporting Items for Systematic Reviews and Meta-Analyses for Scoping Reviews guidelines, a systematic scoping review was conducted up to June 5, 2023.
Plast Reconstr Surg Glob Open
January 2025
Division of Plastic and Reconstructive Surgery, University of Texas Health Science Center San Antonio, San Antonio, TX.
When squamous cell carcinoma necessitates mandibular resection, the resultant defect can be complex. An osteocutaneous fibula free flap is an effective reconstruction option, typically supplied by the peroneal artery for both the fibula and skin flap. In this case report, an anatomical variation was found: the skin paddle was supplied by soleus musculocutaneous perforators of the posterior tibial artery, whereas the fibula was supplied by the peroneal artery.
View Article and Find Full Text PDFIndian J Thorac Cardiovasc Surg
February 2025
Department of Engineering Design, Indian Institute of Technology Madras, Chennai, India.
Purpose: Despite significant improvements in the design and performance of continuous flow left ventricular assist devices (CFLVADs), one of the most important reasons hampering further penetration of this technology is the occurrence of adverse events, especially strokes. One of the well-known risk factors for strokes is hypertension which is particularly common in patients undergoing a CFLVAD implant. While the device is implanted in the heart, strokes happen due to pathology in the brain and we hypothesised that modelling the blood flow in the circle of Willis might shed light on the causation of strokes in this situation.
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